Key takeaways
Zolmitriptan (Zomig) and sumatriptan (Imitrex) are both triptans used to treat migraines, but they have some key differences. Zolmitriptan is available as an oral tablet, orally disintegrating tablet, and nasal spray. Sumatriptan comes as an oral tablet, nasal spray, nasal powder, and under-the-skin injection. Zolmitriptan typically works within 2 hours, whereas sumatriptan can start working in as little as 30 minutes. The maximum daily dose for zolmitriptan is 10 mg, while for sumatriptan, it's 200 mg. Both medications can cause side effects like dizziness and chest pain, but sumatriptan also commonly causes tingling or numbness in fingers or toes. Zolmitriptan is not recommended for people with moderate or severe liver problems, while sumatriptan should be avoided in those with severe liver issues. Both medications are available in generic forms and require a prescription.
