Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Relpax (eletriptan) and naratriptan are both triptans used to treat migraine attacks with or without aura in adults. Relpax is available as a lower-cost generic, while the brand name for naratriptan, Amerge, is no longer available, but you can still get the generic version. You take Relpax at the first sign of a migraine and can repeat the dose after 2 hours if needed, but you can only take up to 80 mg in a day. Naratriptan also requires you to take it at the first sign of a migraine, but you can take a second dose after 4 hours, with a maximum of 5 mg per day. Relpax can take up to 2 hours to reach its full effect, while naratriptan can take up to 4 hours to reach its full effect. Both medications can cause side effects like dizziness and sleepiness, but naratriptan might cause fewer side effects overall. Additionally, Relpax is not recommended for people with severe liver damage, whereas naratriptan should be avoided if you have severe kidney or liver problems.
Eletriptan (Relpax)
Naratriptan
Eletriptan (Relpax)
Naratriptan
Summary of Relpax vs. Amerge
Summary for Triptan
Prescription only
Eletriptan, also known by its brand name Relpax, is a triptan that's a first-choice treatment option for adults who have migraine attacks with or without aura. This medication is available as a tablet that's taken by mouth at the first sign of a migraine attack. The dosage can be repeated 2 hours later if the migraine comes back or doesn't go away. Side effects include making you sleepy and dizzy. Eletriptan (Relpax) is available as a lower-cost generic.
Summary for Triptan
Prescription only
Naratriptan is a triptan that's used to treat migraines with or without aura in adults. While the brand name Amerge is no longer available, there's a generic version that you can get by prescription. Naratriptan is a tablet that's swallowed whole once, typically as a single dose. But you can take the medication again 4 hours later if the first dose didn't work to relieve your migraine. Side effects aren't common, but it might make you nauseous, sleepy, or dizzy.