Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Eletriptan (Relpax) and almotriptan (Axert) are both triptans used to treat migraine attacks. Eletriptan is a generic, while almotriptan is also available in generic form but its brand Axert is no longer available. Eletriptan is typically taken in 20 mg or 40 mg doses, with a maximum of 80 mg per day, and starts working within 30 minutes but can take 2 hours for its full effects. Almotriptan comes in 6.25 mg and 12.5 mg doses, with a maximum of 25 mg per day, and provides relief within 2 hours. Eletriptan is only for adults, whereas almotriptan can be used by children 12 years and older. Both medications can cause side effects like dizziness, sleepiness, nausea, and headache. Eletriptan is not recommended for people with severe liver damage, while almotriptan should be avoided by those with sulfa allergies. Both medications should not be taken more than 10 days per month to avoid worsening headaches.
Eletriptan (Relpax)
Almotriptan
Eletriptan (Relpax)
Almotriptan
Summary of Relpax vs. Axert
Summary for Triptan
Prescription only
Eletriptan, also known by its brand name Relpax, is a triptan that's a first-choice treatment option for adults who have migraine attacks with or without aura. This medication is available as a tablet that's taken by mouth at the first sign of a migraine attack. The dosage can be repeated 2 hours later if the migraine comes back or doesn't go away. Side effects include making you sleepy and dizzy. Eletriptan (Relpax) is available as a lower-cost generic.
Summary for Triptan
Prescription only
Almotriptan is a type of migraine medication called a triptan. It treats migraine with or without aura in adults and certain children age 12 to 17 years. Its brand name Axert has been discontinued, so almotriptan is now only available as a generic. Almotriptan is a tablet that's swallowed whole when a migraine starts. You can take another tablet at least 2 hours later if the medication doesn't completely relieve your migraine. Side effects include sleepiness and headache.