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Compare Ubrelvy vs. Relpax

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ubrelvy (ubrogepant) and Relpax (eletriptan) are both medications used to treat migraine attacks with or without aura in adults. However, they belong to different medication classes. Ubrelvy is a calcitonin gene-related peptide (CGRP) receptor blocker, while Relpax is a triptan. Ubrelvy is taken as a 50 mg or 100 mg oral dose, with a second dose possible after 2 hours if needed, but not exceeding 200 mg per day. Relpax is taken as a 20 mg or 40 mg oral dose, with a second dose possible after 2 hours, but not exceeding 80 mg per day. Ubrelvy is not available as a generic, while Relpax is available in a lower-cost generic form. Common side effects of Ubrelvy include nausea, sleepiness, and dry mouth, whereas Relpax can cause dizziness, sleepiness, and nausea. Ubrelvy interacts with many medications, including certain antibiotics and seizure medications, while Relpax has serious interactions with ergot-containing medications and other triptans. Additionally, Relpax is not typically recommended for people with certain heart conditions or high blood pressure.

  • Ubrelvy (ubrogepant)
    Eletriptan (Relpax)
  • Ubrelvy (ubrogepant)
    Eletriptan (Relpax)

  • Summary of Ubrelvy vs. Relpax

    Summary for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Prescription only

    Ubrelvy (ubrogepant) is a migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It can treat sudden migraine attacks in adults. Ubrelvy (ubrogepant) is a tablet you take by mouth. You take one dose when you feel a migraine starting. If needed, you can take a second dose at least 2 hours later. Your dose depends if Ubrelvy (ubrogepant) interacts with the other medications you take. Side effects include nausea and tiredness.

    Summary for Triptan
    Prescription only

    Eletriptan, also known by its brand name Relpax, is a triptan that's a first-choice treatment option for adults who have migraine attacks with or without aura. This medication is available as a tablet that's taken by mouth at the first sign of a migraine attack. The dosage can be repeated 2 hours later if the migraine comes back or doesn't go away. Side effects include making you sleepy and dizzy. Eletriptan (Relpax) is available as a lower-cost generic.

  • Indications of Ubrelvy vs. Relpax

    Indications for
    •Treatment of migraine attacks with or without aura in adults
    Indications for
    •Treatment of migraine attacks with or without aura in adults

  • Pros and Cons of Ubrelvy vs. Relpax

    Pros and Const for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Pros
    •A tablet that's taken by mouth
    •Helps treat sudden migraine attacks
    •Good option when triptans like sumatriptan (Imitrex) haven't worked well
    Cons
    •Takes 1 to 2 hours to start working
    •Not for preventing migraines
    •Can interact with other medications, like verapamil and phenobarbital
    Pros and Const for Triptan
    Pros
    •Might provide migraine pain relief for a longer period of time than other triptans
    •One of the first-choice options for short-term treatment of migraines
    •Starts to work after 30 minutes
    •Available as a lower-cost, generic
    Cons
    •Only available as a tablet that's swallowed whole
    •Not recommended for people with severe liver damage
    •Not known if it's safe or works well for children
    •Not used for preventing migraines or treating other types of headaches

  • Common Side Effects of Ubrelvy vs. Relpax

    Common Side Effects for
    •Nausea (up to 4%)
    •Sleepiness (up to 3%)
    •Dry mouth (up to 2%)
    Common Side Effects for
    •Dizziness (up to 6%)
    •Sleepiness (up to 6%)
    •Nausea (up to 5%)
    •Body weakness (up to 5%)
    •"Pins and needles" feeling in the arms or legs (3%)

  • Warnings of Ubrelvy vs. Relpax

    Common Side Effects for
    •Allergic reactions
    •High blood pressure
    •Raynaud's phenomenon
    Common Side Effects for
    •Heart problems and high blood pressure
    •Stroke or other brain injury
    •Extreme narrowing of blood vessels
    •Worsened headaches if eletriptan (Relpax) is taken too often
    •Serotonin syndrome

  • Prices with our coupons for Ubrelvy vs. Relpax

    Learn more about Ubrelvy
    Learn more about Eletriptan

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