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Compare Qulipta vs. Ubrelvy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Atogepant (Qulipta) and ubrogepant (Ubrelvy) are both medications that belong to the calcitonin gene-related peptide (CGRP) receptor blocker class and are used to manage migraines in adults. However, they differ in their specific uses and administration. Atogepant is used to prevent migraines and is taken once daily, while ubrogepant is used to treat sudden migraine attacks and can be taken up to twice a day, with doses at least 2 hours apart. Both medications are only available as brand-name products. Common side effects of atogepant include nausea, constipation, and sleepiness, while ubrogepant may cause nausea, sleepiness, and dry mouth. Both can interact with other medications, so it's important to discuss all medications you're taking with a healthcare professional.

  • Qulipta (atogepant)
    Ubrelvy (ubrogepant)
  • Qulipta (atogepant)
    Ubrelvy (ubrogepant)

  • Summary of Qulipta vs. Ubrelvy

    Summary for Calcitonin gene-related peptide (CGRP) receptor blocker
    Prescription only

    Qulipta (atogepant) is a medication that's used to prevent migraines in adults. The specific dosing will depend on how many migraines you have per month, but the medication is typically taken once daily. Qulipta (atogepant) is currently brand only; it isn't available as a lower-cost generic yet. Side effects include nausea, constipation, and sleepiness.

    Summary for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Prescription only

    Ubrelvy (ubrogepant) is a migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It can treat sudden migraine attacks in adults. Ubrelvy (ubrogepant) is a tablet you take by mouth. You take one dose when you feel a migraine starting. If needed, you can take a second dose at least 2 hours later. Your dose depends if Ubrelvy (ubrogepant) interacts with the other medications you take. Side effects include nausea and tiredness.

  • Indications of Qulipta vs. Ubrelvy

    Indications for
    •Prevention of migraines in adults
    Indications for
    •Treatment of migraine attacks with or without aura in adults

  • Pros and Cons of Qulipta vs. Ubrelvy

    Pros and Const for Calcitonin gene-related peptide (CGRP) receptor blocker
    Pros
    •Taken once per day
    •Can take with or without food
    •Can use if you have mild-to-moderate liver problems
    Cons
    •Not used for treating a migraine attack
    •Unknown whether it's safe or works well in children
    •Hasn't been studied in pregnant women
    Pros and Const for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Pros
    •A tablet that's taken by mouth
    •Helps treat sudden migraine attacks
    •Good option when triptans like sumatriptan (Imitrex) haven't worked well
    Cons
    •Takes 1 to 2 hours to start working
    •Not for preventing migraines
    •Can interact with other medications, like verapamil and phenobarbital

  • Common Side Effects of Qulipta vs. Ubrelvy

    Common Side Effects for
    •Nausea (5-9%)
    •Constipation (6-8%)
    •Fatigue or sleepiness (4-5%)
    Common Side Effects for
    •Nausea (up to 4%)
    •Sleepiness (up to 3%)
    •Dry mouth (up to 2%)

  • Warnings of Qulipta vs. Ubrelvy

    Common Side Effects for
    •Allergic reactions
    Common Side Effects for
    •Allergic reactions
    •High blood pressure
    •Raynaud's phenomenon

  • Prices with our coupons for Qulipta vs. Ubrelvy

    Learn more about Qulipta
    Learn more about Ubrelvy

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