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Relpax vs. Ergotamine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Relpax (eletriptan) and Ergomar (ergotamine) are both prescription medications used to treat migraines, but they belong to different drug classes and have distinct characteristics. Relpax is a triptan that works by attaching to serotonin receptors in the brain, tightening blood vessels, and reducing swelling to relieve migraine pain. It is taken orally as a tablet and can be repeated after 2 hours if needed, with a maximum of 80 mg per day. On the other hand, Ergomar is an ergot derivative that also tightens blood vessels but is taken sublingually (under the tongue) and can be repeated after 30 minutes, with a maximum of 6 mg per day and 10 mg per week. Relpax is generally a first-choice treatment for migraines, while Ergomar is not typically a first-choice option but can be used for both migraines and cluster headaches. Relpax can cause side effects like dizziness and sleepiness, whereas Ergomar can cause weakness and vomiting. Additionally, Ergomar is known to cause birth defects and should not be used during pregnancy, while the safety of Relpax during pregnancy is less clear.

Eletriptan

(Relpax)

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Ergomar

(ergotamine)

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Summary for Relpax

Prescription only

Eletriptan, also known by its brand name Relpax, is a triptan that's a first-choice treatment option for adults who have migraine attacks with or without aura. This medication is available as a tablet that's taken by mouth at the first sign of a migraine attack. The dosage can be repeated 2 hours later if the migraine comes back or doesn't go away. Side effects include making you sleepy and dizzy. Eletriptan (Relpax) is available as a lower-cost generic.

Indications for Relpax

Pros and Cons for Relpax

Pros

Cons

  • Only available as a tablet that's swallowed whole
  • Not recommended for people with severe liver damage
  • Not known if it's safe or works well for children
  • Not used for preventing migraines or treating other types of headaches

Common Side Effects for Relpax

  • Dizziness (up to 6%)
  • Sleepiness (up to 6%)
  • Nausea (up to 5%)
  • Body weakness (up to 5%)
  • "Pins and needles" feeling in the arms or legs (3%)

Warnings for Relpax

  • Heart problems and high blood pressure
  • Stroke or other brain injury
  • Extreme narrowing of blood vessels
  • Worsened headaches if eletriptan (Relpax) is taken too often
  • Serotonin syndrome

Summary for Ergotamine

Prescription only

Ergomar (ergotamine) treats migraines. It's an ergot medication. It works by lessening inflammation in the brain and calming certain parts of the brain. Ergomar (ergotamine) is a brand-name medication that comes as sublingual tablets for adults. You place it under the tongue to dissolve as soon as you feel like you're about to have a migraine or headache. Side effects include nausea and vomiting.

Indications for Ergotamine

Pros and Cons for Ergotamine

Pros

  • Dissolves under the tongue, so it's easy to take
  • Can take a second tablet 30 minutes after you first take it if you need more relief
  • Can take on an as-needed basis

Cons

Common Side Effects for Ergotamine

  • Nausea
  • Vomiting
  • Numbness or tingling
  • Weakness

Warnings for Ergotamine

  • Poor blood flow through the body
  • More severe blood circulation problems due to drug interactions
  • Fibrosis (scarring)
  • Harm to an unborn baby

Prices with our coupons for Relpax vs. Ergotamine

Price Card Drug Icon
Eletriptan12 tablets / 40mg
$36.13$346.58
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Price Card Drug Icon
Ergomar20 sublingual tablets / 2mg
$869.44$1,591.57
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