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Emgality Coupon - Emgality 120mg/ml pen

Emgality

galcanezumab
Used for Migraine
Used for Migraine

Emgality (galcanezumab or galcanezumab-gnlm) is a monoclonal antibody that's used to prevent migraine attacks and to treat cluster headaches in adults. Emgality (galcanezumab) works by blocking a specific protein in the brain that can cause migraines and headaches. This medication is injected under the skin monthly. Some common side effects of Emgality (galcanezumab) include pain, itching, and rash at the injection site.

Last reviewed on November 1, 2023
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What is Emgality (galcanezumab)?

What is Emgality (galcanezumab) used for?

How Emgality (galcanezumab) works

Emgality (galcanezumab) is a monoclonal antibody. It blocks a protein in your body called calcitonin gene-related peptide (CGRP) ligand. Your nerves release CGRPs during migraine attacks and cluster headaches. CGRPs cause the blood vessels in your brain to swell, which can lead to pain. When Emgality (galcanezumab) blocks these proteins, it can prevent migraines and ease pain from cluster headaches.

Drug Facts

Common BrandsEmgality
Drug ClassMonoclonal antibody
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Avg retail price
$870.64(save 20.77%)
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$689.84
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What are the side effects of Emgality (galcanezumab)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Pain, itching, warmth, and other injection site reactions (up to 20%)
  • Sore throat, runny nose (up to 18%)
  • Back pain (up to 10%)
Please note: Side effects were reported by people who took Emgality (galcanezumab) in a clinical study.

Other Side Effects

  • Nausea
  • Joint and muscle pain
  • Dizziness
  • Weight gain

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serious allergic reactions: hives, swelling in the face and eyes, swollen throat, trouble breathing, wheezing, nausea, vomiting, diarrhea, dizziness, fainting

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
  • Increase in blood pressure
  • Raynaud syndrome—cool, numb, or painful fingers or toes that may change color from pale, to blue, to red

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Pain, redness, or irritation at injection site
pros-and-cons

Pros and cons of Emgality (galcanezumab)

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Pros

Only needs to be given once a month

Good option for people who have a hard time taking medications by mouth

Patient assistance programs are available to help lower the cost

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Cons

Not a good option for people who don't like needles

Needs to be stored in a refrigerator

Not known whether Emgality (galcanezumab) works well or is safe in young children, or people who are pregnant or breastfeeding

pharmacist-tips

Pharmacist tips for Emgality (galcanezumab)

pharmacist
  • Double check that you received the correct form and dose of Emgality (galcanezumab) before you start treatment. The 120 mg/mL prefilled pens and syringes are used to prevent migraines. The 100 mg/mL prefilled syringes are used to treat cluster headaches.

    • Someone from your care team should train you on how to properly inject this medication at home. Don't try to inject it on your own without instructions.

      Tips on how to store Emgality (galcanezumab):

      • Store Emgality (galcanezumab) in the refrigerator (not in the freezer) in its original container. The original container protects the medication from light. If the medication is exposed to light, it might not work as well.

        • Emgality (galcanezumab) can be stored at room temperature (up to 86°F), away from light, for up to 7 days. Once the medication is stored at room temperature, don't put it back into the refrigerator.

          Tips for preparing for Emgality (galcanezumab) injections:

          • Before you inject Emgality (galcanezumab), leave it at room temperature (up to 86°F) for 30 minutes. Don't warm it up with hot water or with a microwave. This might warm up the medication too much and affect how well it works.

            • Don't shake Emgality (galcanezumab). Shaking it can cause the medication to not work as well.

              • Look at the liquid in your Emgality (galcanezumab) syringe or pen before you use it. It should be colorless, or slightly yellow or slightly brown. Don't use the medication if the color is different. Also don't use it if the liquid looks cloudy or you can see specks floating in it. If you notice these changes, throw away your medication properly.

                Tips on how to inject Emgality (galcanezumab):

                • Inject Emgality (galcanezumab) under the skin of your stomach, thighs, back of the upper arm, or the buttocks. Don't inject in areas that are tender, bruised, red, or hard. If you're giving yourself multiple Emgality (galcanezumab) injections, one right after the other, make sure to choose a different injection site for each injection.

                  • Be sure to throw away used syringes and pens in a sharps container. This will lower the risk of needlestick injuries. If you don't have a sharps container, you can purchase one at your local pharmacy. You can also use a puncture-resistant container as an alternative sharps container, such as an empty laundry detergent bottle.

                    More on Emgality (galcanezumab) tips

                    faqs

                    Frequently asked questions about Emgality (galcanezumab)

                    Do Emgality (galcanezumab) injections hurt?
                    Yes, Emgality (galcanezumab) injections can hurt. But the pain is typically mild or moderate for most people and goes away by the next day. To ease pain, make sure to take the Emgality (galcanezumab) injection out of the refrigerator and let it sit and slowly warm up to room temperature (about 30 minutes) before you inject it. In addition, rotate the injection sites (e.g., back of the arms, thigh, buttocks, or belly) so that you're not injecting the same location repeatedly. If you're continuing to experience injection site pain from Emgality (galcanezumab), talk with your provider. They can double check to see if you're injecting the medication properly and can recommend over-the-counter pain medication, if needed.
                    How long does it take for Emgality (galcanezumab) to work?
                    You might start to notice a difference in the number of migraines you get per month after 1 to 2 months of treatment with Emgality (galcanezumab). People who participated in clinical studies of Emgality (galcanezumab) typically had about 9 migraines per month before starting treatment. After 6 months of treatment, people who took Emgality (galcanezumab) typically experienced 4 to 5 fewer migraines per month, while people who took placebo typically only had about 2-3 fewer migraines monthly. Talk with your provider if you've more questions about how long it takes for Emgality (galcanezumab) to work.
                    Does Emgality (galcanezumab) cause weight gain?
                    It's possible to gain weight while taking Emgality (galcanezumab). People who took Emgality (galcanezumab) during clinical studies reported both weight gain and weight loss, so it's hard to predict exactly how this medication might affect your body weight. Talk with your provider if you're concerned about possible weight gain from Emgality (galcanezumab).
                    Does Emgality (galcanezumab) cause hair loss?
                    Hair loss isn't a side effect reported by people who took Emgality (galcanezumab) during clinical studies. If you experience unexpected hair loss while taking Emgality (galcanezumab), talk with your provider. They can help you figure out what might be causing this problem.
                    What happens if you stop taking Emgality (galcanezumab)?
                    Your provider might ask you to consider stopping Emgality (galcanezumab) if your migraines have been well-controlled for 6 to 12 months. A small study looked at what people experienced after stopping Emgality (galcanezumab) (or other similar medications) after they've been on treatment for 8 to 12 months. Results showed that after stopping treatment, some people started to experience more headaches per month. In addition, some people also noted worsening quality of life, such as avoiding certain activities or having fear of the next migraine attack. Talk with your provider if you want to stop taking Emgality (galcanezumab). They can talk with you about next steps and what to expect.
                    Can you take Emgality (galcanezumab) twice a month?
                    No, Emgality (galcanezumab) is only FDA-approved as a monthly injection and should only be taken as directed by your provider. Talk with your provider if you're not sure how to take your medication.
                    How long can Emgality (galcanezumab) be out of the refrigerator?
                    Once you've left Emgality (galcanezumab) out of the refrigerator, don't put it back in the refrigerator. This medication can be stored at room temperature (up to 86°F) for at most one week. If Emgality (galcanezumab) has been left out at room temperature for longer than one week or if the temperature goes above 86°F, then you should discard it and use a new Emgality (galcanezumab) syringe or prefilled pen.
                    What happens if I missed my dose of Emgality (galcanezumab)?
                    If you missed your regularly monthly dose of Emgality (galcanezumab), inject the missed dose as soon as possible. Keep track of which date you received the injection. You'll inject your next dose one month from this date.
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                    What are the risks and warnings for Emgality (galcanezumab)?

                    Emgality (galcanezumab) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                    risk-warning

                    Serious allergic reactions

                    Emgality (galcanezumab) can cause serious allergic reactions, such as anaphylaxis. This can sometimes happen days after using it. Symptoms can include hives (patches of red, raised skin that might feel hot or itchy), rash, swelling of the face and eyes, swollen throat, trouble breathing, wheezing, cough, trouble swallowing, vomiting, diarrhea, and passing out. If you experience these symptoms, stop Emgality (galcanezumab) and get medical help right away.

                    risk-warning

                    Antibody formation against Emgality (galcanezumab)

                    As with similar medications, it's possible for your body to form antibodies against Emgality (galcanezumab). Based on clinical studies, about 12% of people developed these antibodies after a year of Emgality (galcanezumab) treatment. More research is needed to understand how these antibodies affect the safety of Emgality (galcanezumab) or how well this medication works. Talk with your provider if you're concerned about Emgality (galcanezumab) and antibody formation.

                    dosage

                    Emgality (galcanezumab) dosage forms

                    The average cost for 1 pen of 120mg/ml of Emgality (galcanezumab) is $693.52 with a free GoodRx coupon. This is 20.34% off the average retail price of $870.64.
                    pen
                    Pen
                    DosageQuantityPrice as low asPrice per unit
                    120mg/ml1 pen$693.52$693.52
                    syringe
                    Syringe
                    DosageQuantityPrice as low asPrice per unit
                    100mg/ml3 syringes$1719.57$573.19
                    120mg/ml1 syringe$689.84$689.84

                    Typical dosing for Emgality (galcanezumab)

                    • Migraine prevention: The typical dose is 240 mg (two injections of 120 mg each, one right after the other) injected under the skin once when you first start the medication. Then, inject 120 mg under the skin once a month.

                    • Episodic cluster headaches: The typical dose is 300 mg (three injections of 100 mg each, one right after the other) injected under the skin once at the start of your cluster period. Then, inject 300 mg under the skin once a month, until the end of your cluster period.

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                    alternatives

                    What are alternatives to Emgality (galcanezumab)?

                    There are a number of medications that your doctor can prescribe in place of Emgality (galcanezumab). Compare a few possible alternatives below.
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                    What is the latest news about Emgality (galcanezumab)?

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                    Emgality (galcanezumab) images

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                    References

                    Best studies we found
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