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Taltz vs. Skyrizi

Taltz (ixekizumab) is an injection that's given under the skin. It helps treat inflammatory conditions, including plaque psoriasis, psoriatic arthritis, and some types of arthritis in the spine. This medication works as an interleukin antagonist to lessen inflammation in the body. You inject Taltz (ixekizumab) once a month using the prefilled syringe or autoinjector. The dose depends on the health problem you're treating. Side effects include upper respiratory infections. You also might feel pain or have redness around the injection area. Taltz (ixekizumab) is a brand-name medication.

• Moderate-to-severe plaque psoriasis in people 6 years and older
• Psoriatic arthritis in adults
• Ankylosing spondylitis in adults
• Non-radiographic axial spondyloarthritis in adults

• Reaction at the injection site (e.g., redness, pain; 17%)
• Upper respiratory tract infections (14%)

• Risk of infection
• Caution when getting vaccines
• Eczema-like skin reaction
• Allergic reaction
• Inflammatory bowel disease

Skyrizi (risankizumab or risankizumab-rzaa) is an injectable medication for many inflammatory conditions. It treats plaque psoriasis in adults and children ages 6 years and up. It can also treat psoriatic arthritis, Crohn's disease, and ulcerative colitis in adults. This medication works as an interleukin antagonist to help lower inflammation. After a few starter doses, it's given every 2 or 3 months, depending on the condition being treated. Side effects include a higher risk of infection.

• Moderate-to-severe plaque psoriasis in adults and children ages 6 years and older
• Psoriatic arthritis in adults
• Moderate-to-severe Crohn's disease in adults
• Moderate-to-severe ulcerative colitis in adults

• Upper respiratory infections (13%)
• Headache (4%)
• Tiredness (3%)

• Allergic reaction
• Risk of infection
• Rare case of liver injury
• Caution when getting vaccines