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Compare Taltz vs. Skyrizi

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Taltz (ixekizumab)
    Skyrizi (risankizumab)
  • Taltz (ixekizumab)
    Skyrizi (risankizumab)

  • Summary of Taltz vs. Skyrizi

    Summary for Interleukin antagonist
    Prescription only

    Taltz (ixekizumab) is an injection that's given under the skin. It helps treat inflammatory conditions, including plaque psoriasis, psoriatic arthritis, and some types of arthritis in the spine. This medication works as an interleukin antagonist to lessen inflammation in the body. You inject Taltz (ixekizumab) once a month using the prefilled syringe or autoinjector. The dose depends on the health problem you're treating. Side effects include upper respiratory infections. You also might feel pain or have redness around the injection area. Taltz (ixekizumab) is a brand-name medication.

    Summary for Interleukin antagonist
    Prescription only

    Skyrizi (risankizumab or risankizumab-rzaa) is an injection used to treat different inflammatory conditions in adults. This includes plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. It belongs to the drug class called interleukin antagonists. It works to lower inflammation and relieve symptoms. After the first few doses, you usually get the Skyrizi (risankizumab) injection every 2 or 3 months. This medication can raise your risk of infection as a side effect.

  • Indications of Taltz vs. Skyrizi

    Indications for
    •Moderate-to-severe plaque psoriasis in people 6 years and older
    •Psoriatic arthritis in adults
    •Ankylosing spondylitis in adults
    •Non-radiographic axial spondyloarthritis in adults
    Indications for
    •Moderate-to-severe plaque psoriasis in adults
    •Psoriatic arthritis in adults
    •Moderate-to-severe Crohn's disease in adults
    •Moderate-to-severe ulcerative colitis in adults

  • Pros and Cons of Taltz vs. Skyrizi

    Pros and Const for Interleukin antagonist
    Pros
    •Generally given once a month (might need some starter doses)
    •Available as a prefilled syringe or autoinjector for easier use
    •Can inject at home after a healthcare professional trains you (for most people)
    Cons
    •Only given as an injection under the skin
    •Raises the risk of infections
    •Might cause flare-ups in people with Crohn's disease or ulcerative colitis
    Pros and Const for Interleukin antagonist
    Pros
    •Given every 2 or 3 months after a couple of starter doses (depends on your condition)
    •Can give injections under the skin at home after you get trained
    Cons
    •Must be given as an injection
    •Not approved for children

  • Common Side Effects of Taltz vs. Skyrizi

    Common Side Effects for
    •Reaction at the injection site (e.g., redness, pain; 17%)
    •Upper respiratory tract infections (14%)
    Common Side Effects for
    •Upper respiratory infections (13%)
    •Headache (4%)
    •Tiredness (3%)

  • Warnings of Taltz vs. Skyrizi

    Common Side Effects for
    •Risk of infection
    •Caution when getting vaccines
    •Eczema-like skin reaction
    •Allergic reaction
    •Inflammatory bowel disease
    Common Side Effects for
    •Allergic reaction
    •Risk of infection
    •Rare case of liver injury
    •Caution when getting vaccines

  • Prices with our coupons for Taltz vs. Skyrizi

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    Learn more about Skyrizi

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