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Qulipta vs. Nurtec

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Atogepant (Qulipta) and rimegepant (Nurtec ODT) are both prescription medications used to prevent migraines in adults. They are both calcitonin gene-related peptide (CGRP) receptor blockers. However, they have some differences. Atogepant is only used for preventing migraines and is taken as a tablet once daily, while rimegepant can both prevent and treat migraines and is taken every other day for prevention or as needed for treatment. Both medications are only available in a branded version. Common side effects of atogepant include nausea, constipation, and sleepiness, while rimegepant may cause nausea and stomach pain. Both medications can cause serious allergic reactions and can interact with grapefruit juice. Both medications have many interactions, so be sure your prescriber and pharmacist have a complete list of all the medications you take.

Qulipta

(atogepant)

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Nurtec ODT

(rimegepant)

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Summary for Qulipta

Prescription only

Qulipta (atogepant) is a medication that's used to prevent migraines in adults. The specific dosing will depend on how many migraines you have per month, but the medication is typically taken once daily. Qulipta (atogepant) is currently brand only; it isn't available as a lower-cost generic yet. Side effects include nausea, constipation, and sleepiness.

Indications for Qulipta

  • Prevention of migraines in adults

Pros and Cons for Qulipta

Pros

  • Taken once per day
  • Can take with or without food
  • Can use if you have mild-to-moderate liver problems

Cons

  • Not used for treating a migraine attack
  • Unknown whether it's safe or works well in children
  • Hasn't been studied in pregnant women

Common Side Effects for Qulipta

  • Nausea (5-9%)
  • Constipation (6-8%)
  • Fatigue or sleepiness (4-5%)

Warnings for Qulipta

  • Allergic reactions

Summary for Nurtec

Prescription only

Nurtec ODT (rimegepant) is a type of migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It helps treat migraine attacks with or without aura in adults. It can also help prevent migraines from happening in the long run. This medication is an orally disintegrating tablet (ODT). You put it on or under the tongue and let it dissolve. The dosage is 1 tablet each time. But how often you take the medication depends on if you're taking it to prevent or treat migraines. Side effects include nausea and stomach pain. Nurtec ODT (rimegepant) is a brand-name medication; there's no generic version yet.

Indications for Nurtec

  • Treatment of migraines with or without aura in adults
  • Prevention of migraines with or without aura in adults

Pros and Cons for Nurtec

Pros

Cons

Common Side Effects for Nurtec

  • Nausea (up to 3%)
  • Stomach pain or indigestion (up to 2%)

Warnings for Nurtec

  • Allergic reactions
  • High blood pressure
  • Raynaud's phenomenon

Prices with our coupons for Qulipta vs. Nurtec

Price Card Drug Icon
Qulipta30 tablets / 60mg
$1,114.07$1,463.66
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Price Card Drug Icon
Nurtec1 dose pack / 8 orally disintegrating tablets of 75mg
$480.00$1,229.71
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