Key takeaways
Prezcobix (darunavir/cobicistat) and Triumeq (abacavir/dolutegravir/lamivudine) are both medications used to treat HIV, but they have some key differences. Prezcobix combines two drugs: darunavir, a protease inhibitor, and cobicistat, a booster that helps darunavir work better. It's taken once daily with food and is suitable for adults and children weighing at least 88 pounds. Triumeq, on the other hand, is a single-tablet regimen that includes three drugs: abacavir and lamivudine, both nucleoside reverse transcriptase inhibitors (NRTIs), and dolutegravir, an integrase inhibitor. Triumeq can be taken with or without food and is available for adults and children weighing at least 22 pounds. Before starting Triumeq, you need a genetic test to check for a specific trait that could cause a severe allergic reaction, which is not required for Prezcobix. Additionally, Triumeq is not recommended for people with severe liver problems, while Prezcobix must be used carefully in people with sulfa allergies and is not recommended during pregnancy. Both medications interact with many other drugs, so it's important to discuss all your medications with your healthcare provider.
