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Osteoporosis Medications

Find prices and information on Osteoporosis medications.

Read our guide toOsteoporosis

Key takeaways

Medications for osteoporosis are used to strengthen bones and reduce the risk of fractures. They work by either slowing down bone loss or increasing bone formation. Common classes include bisphosphonates, selective estrogen receptor modulators (SERMs), and RANK ligand (RANKL) inhibitor. Bisphosphonates like alendronate (Fosamax) and ibandronate are usually taken as oral pills but can also be given as injections. SERMs, such as raloxifene (Evista), are typically taken as oral pills. RANKL inhibitor, such as Prolia (denosumab) come as an injection. These medications offer different ways to help maintain your bone health.

Prices for popular Osteoporosis medications
Viewing 25 of 29 medications
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Premarin

as low as$99
View otherEstrogens
Premarin (conjugated estrogens) is used to treat hot flashes and prevent osteoporosis, low hormone levels or in those who have had their ovaries removed. Premarin is covered by most Medicare and insurance plans.
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Estradiol (Estrace, Vivelle-Dot, Climara) is a moderately priced drug used to treat hot flashes and osteoporosis. It is also used to treat women with low estrogen levels or those who have had their ovaries removed. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions. It is covered by some Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Estradiol (Estrace, Vivelle-Dot, Climara) is a moderately priced drug used to treat hot flashes and osteoporosis. It is also used to treat women with low estrogen levels or those who have had their ovaries removed. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions. It is covered by some Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Estradiol (Estrace, Vivelle-Dot, Climara) is a moderately priced drug used to treat hot flashes and osteoporosis. It is also used to treat women with low estrogen levels or those who have had their ovaries removed. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions. It is covered by some Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Menostar (estradiol) is an expensive drug used to prevent osteoporosis in postmenopausal women. It is less popular than comparable drugs. There is currently no generic version available. Menostars covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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ibuprofen

as low as$8
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Ibuprofen is an NSAID used to treat fever and pain from arthritis, menstrual cramps, and muscular aches. It works by reducing inflammation. Ibuprofen is a generic medication, and is available both over-the-counter and by prescription depending on the strength. Prescription Motrin had the same active ingredient, but has been discontinued. Over-the-counter brands include Advil and Motrin IB. Ibuprofen should be used only when needed as it may increase risk of stroke or heart attack and long term use can cause stomach bleeding and ulcers.
View otherBisphosphonates
Alendronate (Fosamax) slows calcium loss from bones. It helps to make normal healthy bone and to slow bone loss in people with Paget's disease and osteoporosis. It may be used in others at risk for bone loss. It is more popular than comparable drugs. It is available in generic and brand versions. Generic alendronate is covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can offset the cost.
View otherBisphosphonates
IBANDRONATE prevents and treats osteoporosis. It works by making your bones stronger and less likely to break (fracture). It belongs to a group of medications called bisphosphonates.
View otherCalcitonins
CALCITONIN treats osteoporosis. It may also be used to treat Paget's disease of the bone. It works by making your bones stronger and less likely to break (fracture). It can also be used to treat high calcium levels in your body. It works by blocking the breakdown of bone calcium and helping your kidneys remove calcium from your blood through the urine.
View otherBisphosphonates
Reclast (zoledronic acid) is an expensive drug used to treat Paget's disease and osteoporosis in women. It is less popular than comparable drugs. There are currently no generic alternatives to Reclast. The most common version of Reclast is covered by 98% of insurance plans at a co-pay of $60.00-$82.50, however, some pharmacy coupons or cash prices may be lower.
RALOXIFENE prevents and treats osteoporosis after menopause. It works by making your bones stronger and less likely to break (fracture). It may also be used to lower the risk of breast cancer in people with osteoporosis or who are at high risk of breast cancer after menopause. It works by blocking the hormone estrogen in breast tissue, which prevents breast cancer cells from spreading or growing.
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Lyllana

as low as$34
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ESTRADIOL reduces the number and severity of hot flashes due to menopause. It may also help relieve the symptoms of menopause, such as vaginal irritation, dryness, or pain during sex. It can also be used to prevent osteoporosis after menopause. It works by increasing levels of the hormone estrogen in the body. This medication is an estrogen hormone.
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jinteli

as low as$45
NORETHINDRONE ACETATE; ETHINYL ESTRADIOL reduces the number and severity of hot flashes due to menopause. It may be used to prevent osteoporosis after menopause. It works by increasing levels of the hormone estrogen in the body, which decreases the symptoms of menopause. It also prevents the lining of the uterus from becoming too thick, which decreases the risk of cancer of the uterus. It is a combination of the hormones estrogen and progestin.
ESTRADIOL; NORETHINDRONE relieves the symptoms of menopause, such as hot flashes or vaginal dryness. It may also be used to prevent osteoporosis. It works by increasing levels of the hormones estrogen and progestin in your body. It is a combination of the hormones estrogen and progestin.
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ESTRADIOL relieves the symptoms of menopause, such as hot flashes or vaginal dryness. It may also be used to treat low estrogen levels. It is also used to reduce the symptoms of prostate cancer. It works by increasing levels of the hormone estrogen in the body. This medication is an estrogen hormone.
View otherBisphosphonates
RISEDRONATE prevents and treats osteoporosis. It may also be used to treat Paget's disease of the bone. It works by making your bones stronger and less likely to break (fracture). It belongs to a group of medications called bisphosphonates.
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Prempro

as low as$99
Prempro (conjugated estrogens; medroxyprogesterone) is used as hormone replacement in menopausal women who still have their uterus, treats hot flashes and prevents osteoporosis. This drug is slightly more popular than other estrogen/progestin combinations.
There are currently no generic alternatives to Prempro.

Prempro is covered by most Medicare and insurance plans.
Exclusive manufacturer discount
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Duavee

as low as$99
Duavee (conjugated estrogens/bazedoxifene) is used to treat hot flashes and prevent osteoporosis. There are currently no generic alternatives to Duavee. Duavee is covered by most Medicare and insurance plans.
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Alora

as low as$106
View otherEstrogens
ESTRADIOL reduces the number and severity of hot flashes due to menopause. It may also help relieve the symptoms of menopause, such as vaginal irritation, dryness, or pain during sex. It can also be used to prevent osteoporosis after menopause. It works by increasing levels of the hormone estrogen in the body. This medication is an estrogen hormone.
ALENDRONATE; CHOLECALCIFEROL treats osteoporosis. It works by making your bones stronger and less likely to break (fracture). It is a combination of a bisphosphonate and a form of vitamin D.
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Premphase

as low as$237
Premphase (conjugated estrogens; medroxyprogesterone) is used as hormone replacement in menopausal women who still have their uterus, treat hot flashes and prevent osteoporosis. This drug is slightly less popular than other estrogen/progestin combinations. There are currently no generic alternatives to Premphase.

GoodRx has partnered with InsideRx and Pfizer to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Premphase is covered by most Medicare and insurance plans.
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Binosto

as low as$238
View otherBisphosphonates
ALENDRONATE treats osteoporosis. It works by making your bones stronger and less likely to break (fracture). It belongs to a group of medications called bisphosphonates.
ESTRADIOL; LEVONORGESTREL reduces the number and severity of hot flashes due to menopause. It may be used to prevent osteoporosis after menopause. It works by increasing levels of the hormones estrogen and progestin in your body. It is a combination of the hormones estrogen and progestin.
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Atelvia

as low as$261
View otherBisphosphonates
RISEDRONATE treats osteoporosis. It works by making your bones stronger and less likely to break (fracture). It belongs to a group of medications called bisphosphonates.
Teriparatide Injection is part of the Parathyroid Hormones class and treats Osteoporosis. Parathyroid hormones are used to treat osteoporosis. They work by strengthening the bones and preventing breakage. Teriparatide Injection is only available as a generic drug.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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