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Compare Provera vs. Danazol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Medroxyprogesterone (Provera) and danazol are both prescription medications, but they serve different purposes and belong to different drug classes. Medroxyprogesterone is a progestin used to regulate menstrual cycles and protect the uterus from damage in postmenopausal women taking estrogen replacement medication. Danazol, on the other hand, is a gonadotropin inhibitor used to treat endometriosis and hereditary angioedema. Medroxyprogesterone is typically taken once a day for a short duration each month, while danazol is taken itwo to three times a day depending on why you are taking it. Danazol is not a first-choice treatment for endometriosis due to its side effects, which include acne, weight gain, and a deeper voice. Additionally, danazol can cause serious issues like liver damage and blood clots. Medroxyprogesterone can also have side effects like spotting and breast tenderness, but it is generally well-tolerated.

  • Medroxyprogesterone (Provera)
    Danazol
  • Medroxyprogesterone (Provera)
    Danazol

  • Summary of Provera vs. Danazol

    Summary for Progestin
    Prescription only

    Medroxyprogesterone (Provera) can help make your menstrual cycles more regular. It also helps protect the uterus from harm in people who've gone through menopause and are taking estrogen replacement medications. When taken with estrogen therapy, it has some serious risks that you should consider if you need treatment for a long time.

    Summary for Gonadotropin inhibitor
    Prescription only

    Danazol treats endometriosis (a painful condition involving the tissue of your uterus), but it's not a first-choice medication because of the side effects.

  • Indications of Provera vs. Danazol

    Indications for
    •Lack of menstrual periods due to hormone imbalance
    •Irregular periods due to hormone imbalance
    •Protection of the uterus in postmenopausal women who are taking estrogen medications
    Indications for
    •Endometriosis (extra tissue growth in and around your uterus)
    •Hereditary angioedema (inherited condition that causes swelling in your lips and other body parts)

  • Pros and Cons of Provera vs. Danazol

    Pros and Const for Progestin
    Pros
    •Taken once a day
    •Helps protect the uterus from damage if taking estrogen medications after menopause
    •A good alternative to progesterone (Prometrium) if you have a peanut allergy
    Cons
    •Need to remember to take on certain days of the month
    •Can have spotting or breakthrough bleeding, even if you've gone through menopause
    •Shouldn't be used in people with liver problems
    Pros and Const for Gonadotropin inhibitor
    Pros
    •Works well to treat the pain caused from endometriosis
    •Medication available in a generic form which may make it more affordable
    Cons
    •Can't use during pregnancy
    •Not a cure for endometriosis

  • Common Side Effects of Provera vs. Danazol

    Common Side Effects for
    •Spotting or breakthrough bleeding
    •Heavier or lighter periods
    •Breast tenderness
    •Nausea
    Common Side Effects for
    •Weight gain
    •Acne
    •Swelling
    •Deepening of voice
    •Sweating or flushing

  • Warnings of Provera vs. Danazol

    Common Side Effects for
    •When taken with estrogen medications:
    •Blood clots and their complications (heart attack, stroke)
    •Breast cancer
    •Dementia
    •Uterine and ovarian cancer
    •Vision problems
    •Higher blood pressure and cholesterol levels
    •Swelling (fluid buildup)
    Common Side Effects for
    •Pregnancy and breastfeeding
    •Risk of blood clots
    •Liver disease
    •Increased pressure in the brain

  • Prices with our coupons for Provera vs. Danazol

    Learn more about Medroxyprogesterone
    Learn more about Danazol

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