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Estrogen Agonist/Antagonists

Estrogen agonist/antagonists are used for fertility, breast cancer, PCOS, and osteoporosis. They work by changing hormone levels in the body.

Why are estrogen agonist antagonists prescribed?

  1. Fertility (45%)
  2. PCOS (45%)
  3. Osteoporosis (4%)
  4. Breast Cancer (4%)
  5. Menopause (2%)
  6. Atrophic Vaginitis (1%)

Key takeaways

Estrogen agonist / antagonists are used to treat symptoms of menopause and treat or prevent osteoporosis. They also have other uses, such as managing infertility and treating breast cancer. These medications work by either blocking or activating estrogen receptors in different tissues, which helps to balance the effects of estrogen in your body. They come as oral tablets. Examples include raloxifene (Evista), ospemifene (Osphena), and clomiphene (Clomid). You can discuss with your healthcare team which option might be right for you.

Prices for popular Estrogen Agonist/Antagonists medications
Viewing 5 of 5 medications
Clomid (clomiphene) is used to treat ovulatory dysfunction in women trying to conceive, such as those with PCOS. Clomid is an estrogen agonist/antagonist, which works by changing hormone levels in the body. Clomid is avalible as a tablet. There is currently a generic for Clomid, but it is being phased out. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost.
RALOXIFENE prevents and treats osteoporosis after menopause. It works by making your bones stronger and less likely to break (fracture). It may also be used to lower the risk of breast cancer in people with osteoporosis or who are at high risk of breast cancer after menopause. It works by blocking the hormone estrogen in breast tissue, which prevents breast cancer cells from spreading or growing.
Exclusive manufacturer discount
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Duavee

as low as$99
Duavee (conjugated estrogens/bazedoxifene) is used to treat hot flashes and prevent osteoporosis. There are currently no generic alternatives to Duavee. Duavee is covered by most Medicare and insurance plans.
Exclusive manufacturer discount
tablet icon

Osphena

as low as$99
Osphena (ospemifene) is used to treat vaginal dryness and painful sexual intercourse due to menopause. There are currently no generic alternatives for Osphena.

GoodRx has partnered with InsideRx and Duchesnay USA to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Osphena is covered by some Medicare and insurance plans.
TOREMIFENE treats breast cancer. It works by blocking the hormone estrogen in breast tissue, which prevents breast cancer cells from spreading or growing.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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