Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Clomiphene (Clomid) and Exemestane (Aromasin) are both prescription medications, but they serve different purposes and belong to different drug classes. Clomiphene is a selective estrogen receptor modulator (SERM) used to treat female infertility by inducing ovulation, especially in those with polycystic ovary syndrome (PCOS). It is taken orally for just 5 days during the menstrual cycle. On the other hand, Exemestane is an aromatase inhibitor used to treat breast cancer in postmenopausal women by lowering estrogen levels in the body. It is also taken orally but needs to be taken once daily after a meal. While Clomiphene can cause side effects like hot flashes and stomach pain, Exemestane can lead to hot flashes, joint pain, and weakened bones. Additionally, Exemestane requires regular blood tests to monitor for side effects, whereas Clomiphene does not.
Clomid (clomiphene)
Exemestane (Aromasin)
Clomid (clomiphene)
Exemestane (Aromasin)
Summary of Clomid vs. Aromasin
Summary for Selective estrogen receptor modulator
Prescription only
Clomid (clomiphene) is a selective estrogen receptor modulator (SERM) used to treat infertility in people wanting to become pregnant. It works by causing ovulation, or egg release. You'll take a dose by mouth every day for 5 days, typically during your menstrual period. Some of the more common side effects include hot flashes, bloating, and stomach pain.
Summary for Aromatase inhibitor
Prescription only
Exemestane, also known by its brand name Aromasin, is an oral medication that’s used for treating certain types of breast cancer in people who’ve gone through menopause. It’s a form of hormonal therapy called an aromatase inhibitor that lowers the amount of estrogen in the body. Exemestane (Aromasin) is a tablet that's taken once a day. But it can cause side effects like hot flashes and tiredness.