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Clomid vs. Aromasin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Clomiphene (Clomid) and Exemestane (Aromasin) are both prescription medications, but they serve different purposes and belong to different drug classes. Clomiphene is a selective estrogen receptor modulator (SERM) used to treat female infertility by inducing ovulation, especially in those with polycystic ovary syndrome (PCOS). It is taken orally for just 5 days during the menstrual cycle. On the other hand, Exemestane is an aromatase inhibitor used to treat breast cancer in postmenopausal women by lowering estrogen levels in the body. It is also taken orally but needs to be taken once daily after a meal. While Clomiphene can cause side effects like hot flashes and stomach pain, Exemestane can lead to hot flashes, joint pain, and weakened bones. Additionally, Exemestane requires regular blood tests to monitor for side effects, whereas Clomiphene does not.

Clomid

(clomiphene)

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Exemestane

(Aromasin)

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Summary for Clomid

Prescription only

Clomid (clomiphene) is a selective estrogen receptor modulator (SERM) used to treat infertility in people wanting to become pregnant. It works by causing ovulation, or egg release. You'll take a dose by mouth every day for 5 days, typically during your menstrual period. Some of the more common side effects include hot flashes, bloating, and stomach pain.

Indications for Clomid

Pros and Cons for Clomid

Pros

Cons

  • Typically only recommended for up to 3 cycles, not a long-term treatment
  • Can cause vision problems in some rare cases
  • Not safe if you have liver problems or certain thyroid problems

Common Side Effects for Clomid

  • Swollen ovaries (14%)
  • Hot flashes (10%)
  • Stomach pain, discomfort, or bloating (6%)

Warnings for Clomid

  • Vision changes
  • Ovarian hyperstimulation syndrome (OHSS)
  • Possible risk of harm to unborn baby

Summary for Aromasin

Prescription only

Exemestane, also known by its brand name Aromasin, is an oral medication that’s used for treating certain types of breast cancer in people who’ve gone through menopause. It’s a form of hormonal therapy called an aromatase inhibitor that lowers the amount of estrogen in the body. Exemestane (Aromasin) is a tablet that's taken once a day. But it can cause side effects like hot flashes and tiredness.

Indications for Aromasin

  • Early breast cancer in postmenopausal women who've had 2 to 3 years of treatment with tamoxifen
  • Advanced breast cancer in postmenopausal women whose cancer has worsened following treatment with tamoxifen

Pros and Cons for Aromasin

Pros

Cons

  • Can cause menopausal symptoms, such as hot flashes and sweating
  • Can weaken your bones over time
  • Requires regular blood tests and follow-ups so your oncologist can check for side effects

Common Side Effects for Aromasin

  • Hot flashes (21%)
  • Fatigue (16%)
  • Joint pain (15%)
  • Headache (13%)
  • Trouble sleeping (12%)
  • Sweating more often or being sweatier (12%)
  • Dizziness (10%)
  • High blood pressure (10%)

Warnings for Aromasin

  • Low vitamin D levels
  • Weakened bones
  • Changes in lab results related to kidney or liver health
  • Low blood cell counts
  • Harm to unborn baby

Prices with our coupons for Clomid vs. Aromasin

Price Card Drug Icon
Clomid30 tablets / 50mg
$111.49-
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Exemestane30 tablets / 25mg
$32.84$497.50
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