Skip to main content

Estrogen / Progestin Combinations

Estrogen / progestin combinations are used for birth control, estrogen replacement, and to treat menopause, osteoporosis, PMDD, and acne. They work by preventing ovulation, increasing estrogen levels, and changing hormone levels.

Why are estrogen progestin combinations prescribed?

  1. Birth Control (80%)
  2. PMDD (5%)
  3. Acne (5%)
  4. Menopause (5%)
  5. Osteoporosis (4%)
  6. Osteoarthritis (0%)
  7. Estrogen Replacement (0%)

Key takeaways

Estrogen / progestin combinations are used to prevent pregnancy, manage menstrual disorders, and treat acne. Certain medications in this class can be used to treat symptoms of menopause. These medications work by regulating estrogen and progesterone levels in the body. Before menopause, this helps prevent pregnancy and treat menstrual disorders. During and after menopause, regulating hormone levels helps relieve symptoms such as hot flashes and night sweats. Estrogen / progestin combinations come in different forms, including oral pills and vaginal rings. Examples include norgestimate / ethinyl estradiol (Sprintec), drospirenone / ethinyl estradiol (Yaz), etonogestrel / ethinyl estradiol (NuvaRing), and desogestrel / ethinyl estradiol (Apri). You can discuss with your healthcare team which option might be right for you.

Prices for popular Estrogen / Progestin Combinations medications
Viewing 25 of 55 medications
package icon

estarylla, femynor, mili, mono-linyah, norgestimate / ethinyl estradiol, nymyo, previfem, sprintec, vylibra

as low as$18
norgestimate/ethinyl estradiol (sprintec, estarylla, femynor, mili, mono-linyah, previfem, vylibra, nymyo) is a moderately priced oral contraceptive. They are used to prevent ovulation and pregnancy. Some products are also used to treat acne. It is available in multiple generic and brand versions. Generic norgestimate/ethinyl estradiol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
package icon

drospirenone / ethinyl estradiol

as low as$13
DROSPIRENONE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It may also be used to treat acne and premenstrual dysphoric disorder (PMDD). It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

Yaz (jasmiel, lo-zumandimine, loryna, nikki, vestura)

as low as$28
DROSPIRENONE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It may also be used to treat acne and premenstrual dysphoric disorder (PMDD). It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

Delyla (afirmelle, aubra, aviane, falmina, larissia, lutera, orsythia, vienva)

as low as$12
LEVONORGESTREL; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

tri-estarylla, tri-femynor, tri-linyah, tri-mili, tri-nymyo, tri-previfem, tri-sprintec, tri-vylibra

as low as$22
NORGESTIMATE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It may also be used to treat acne. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
ring icon

NuvaRing (EluRyng, enilloring, etonogestrel / ethinyl estradiol, haloette)

as low as$39
Ethinyl estradiol/etonogestrel (Eluryng, Nuvaring) is a moderately priced drug used to prevent pregnancy. Nuvaring is an estrogen/progestin combination, and works by preventing ovulation. It is slightly more popular than comparable drugs. It is available as a ring. It is available in generic and brand versions. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
package icon

altavera, ayuna, chateal, kurvelo, levora, lillow, marlissa, portia

as low as$10
LEVONORGESTREL; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

Loestrin 1/20 (aurovela 1/20, junel 1/20, larin 1/20, microgestin 1/20)

as low as$10
Norethindrone acetate/ethinyl estradiol (aurovela 1/20, junel 1/20, gildess 1/20, larin 1/20, loestrin 1/20, microgestin 1/20, ) is an affordable oral contraceptive. They are used to prevent ovulation and pregnancy. Some products are also used to treat acne. It is available in multiple generic and brand versions. Generic norgestimate/ethinyl estradiol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
See pricesMore info
package icon

cyred, emoquette, enskyce, isibloom

as low as$11
DESOGESTREL; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

tri-lo-estarylla, tri-lo-mili, tri-vylibra LO

as low as$11
Ethinyl estradiol/norgestimate (tri-lo marzia, tri-lo estarylla, tri-lo sprintec, tri-lo-mili, tri-vylibra-lo) is a moderately priced drug used to prevent ovulation and pregnancy. This drug is more popular than comparable drugs. It is available in multiple brand and generic versions. It is not covered by most Medicare and insurance plans, but some manufacturer and pharmacy coupons can help offset the cost.
See pricesMore info
package icon

apri, cyred EQ, desogestrel / ethinyl estradiol, emoquette, enskyce, isibloom, juleber, kalliga, reclipsen

as low as$12
DESOGESTREL; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

tri-lo-marzia, tri-lo-mili, tri-lo-sprintec, tri-vylibra LO

as low as$22
Ethinyl estradiol/norgestimate (tri-lo marzia, tri-lo estarylla, tri-lo sprintec, tri-lo-mili, tri-vylibra-lo) is a moderately priced drug used to prevent ovulation and pregnancy. This drug is more popular than comparable drugs. It is available in multiple brand and generic versions. It is not covered by most Medicare and insurance plans, but some manufacturer and pharmacy coupons can help offset the cost.
See pricesMore info
package icon

ethinyl estradiol/norethindrone, oshih

as low as$26
NORETHINDRONE ACETATE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

norelgestromin / ethinyl estradiol, xulane, zafemy

as low as$47
ETHINYL ESTRADIOL;NORELGESTROMIN prevents ovulation and pregnancy. It belongs to a group of medications called contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

Activella (amabelz, estradiol / norethindrone, etyqa, lopreeza, mimvey)

as low as$56
ESTRADIOL; NORETHINDRONE relieves the symptoms of menopause, such as hot flashes or vaginal dryness. It may also be used to prevent osteoporosis. It works by increasing levels of the hormones estrogen and progestin in your body. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

averi, desogestrel / ethinyl estradiol, enskyce, isibloom, kalliga

as low as$206
Averi is part of the Estrogen / Progestin Combinations class and treats Birth Control. Estrogen / progestin combinations are used for birth control, estrogen replacement, and to treat menopause, osteoporosis, PMDD, and acne. They work by preventing ovulation, increasing estrogen levels, and changing hormone levels. Averi is only available as a generic drug.
See prices
package icon

alyacen 7/7/7, cyclafem 7/7/7, dasetta 7/7/7, necon 7/7/7, nortrel 7/7/7, nylia 7/7/7, pirmella 7/7/7

as low as$9
NORETHINDRONE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

cyonanz, necon 0.5/35, nortrel 0.5/35, wera

as low as$10
Cyonanz is part of the Estrogen / Progestin Combinations class and treats Birth Control. Estrogen / progestin combinations are used for birth control, estrogen replacement, and to treat menopause, osteoporosis, PMDD, and acne. They work by preventing ovulation, increasing estrogen levels, and changing hormone levels. Cyonanz is only available as a generic drug.
See pricesMore info
package icon

ethynodiol diacetate/ethinyl estradiol

as low as$11
ETHYNODIOL DIACETATE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

enpresse, ethinyl estradiol/levonorgestrel, levonest, myzilra, trivora

as low as$12
LEVONORGESTREL; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

kelnor, zovia

as low as$13
ETHYNODIOL DIACETATE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

Loestrin 21 1.5/30 (aurovela 1.5/30, hailey 1.5/30, junel 1.5/30, larin 1.5/30, microgestin 1.5/30)

as low as$13
NORETHINDRONE ACETATE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

aranelle, leena

as low as$14
NORETHINDRONE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

azurette, bekyree, desogestrel / ethinyl estradiol / ethinyl estradiol, kariva, pimtrea, simliya, viorele, volnea

as low as$14
DESOGESTREL; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
package icon

balziva, briellyn, philith, rhuzdah, vyfemla, zenchent

as low as$16
NORETHINDRONE; ETHINYL ESTRADIOL prevents ovulation and pregnancy. It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
See pricesMore info
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Subscribe and save

Get prescription saving tips and more from GoodRx Health. Enter your email to sign up

By signing up, I agree to GoodRx’s Terms of Use and Privacy Policy, and to receive marketing messages from GoodRx.

Latest Articles

closeup birth control packets 696585930

What’s the Best Birth Control Pill? How to Pick a Birth Control Brand That’s Right for You

Andrea Kemp, MD, MPHUpdated on Feb 28, 2025
Birth control: holding birth control pack 1330013390

9 Things to Know About Birth Control Interactions With Dietary Supplements and Herbal Remedies

Tegan Smedley, PharmD, APhUpdated on Sep 10, 2024
birth-control: closeup slicing grapefruit 1313810625

What Foods Affect Birth Control Pills? 5 Pharmacist-Backed Answers to Birth Control FAQs

Kristine Foley, PharmDPublished on Sep 3, 2024
Health: Womens Health: GettyImages 1155758407

What Causes Vaginal Dryness, and How Can You Treat It?

Maryann Mikhail, MDUpdated on May 15, 2024
Annovera: four contraceptive rings holding one-1329750785

What Is Annovera? How It Works, Side Effects, and Efficacy

Christina Aungst, PharmDUpdated on Nov 6, 2023
Health: Birth Control: GettyImages 1291732873

5 Lesser-Known Birth Control Side Effects

Cydnee Ng, PharmDUpdated on Apr 24, 2023
Health: Birth Control: GettyImages 1292165452

What are the Risks and Side Effects of Birth Control Pills?

Christina Aungst, PharmDUpdated on Apr 12, 2023
Birth control: Most prescribed: colorful birth control pile-821771566

Sprintec, Junel FE, and Apri: How Do These Popular Birth Control Pills Compare?

Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMPUpdated on Sep 13, 2022
Can Your Birth Control Cause Blood Clots? An OB-GYN Explains
Video play button

What You Need to Know About Birth Control and Blood Clot Risk

0:58
Updated on Aug 2, 2022
birth-control: hands-holding-birth-control-pills-871189318

Birth Control Insurance Coverage: How to Get Contraception With or Without Insurance

Kristen FischerUpdated on Jul 27, 2022
Health: Birth Control: GettyImages-1221479908

What Are My Birth Control Options If I Don’t Have Insurance?

Christina Aungst, PharmDUpdated on Jul 26, 2022
Health: birth control: tan hand holding birth control pill pack-1288605120

Beyaz vs. Yaz Birth Control Pills: What to Know

Ross Phan, PharmD, BCACP, BCGP, BCPSUpdated on Apr 22, 2022
Health: estradiol: shutterstock 1542440486

Estrogen Patches: What You Should Know

Ross Phan, PharmD, BCACP, BCGP, BCPSUpdated on Mar 21, 2022
Blog banner: dollars-pill-bottle-pattern-goodrx.png

Over 600 Drugs Saw Price Hikes in January – What Does It Mean for Consumers?

Tori Marsh, MPHPublished on Feb 6, 2020

Browse medications

View All
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.
ABCDEFGHIJKLMNOPQRSTUVWXYZ