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Premphase (conjugated estrogens; medroxyprogesterone) is used as hormone replacement in menopausal women who still have their uterus, treat hot flashes and prevent osteoporosis. This drug is slightly less popular than other estrogen/progestin combinations. There are currently no generic alternatives to Premphase.
GoodRx has partnered with InsideRx and Pfizer to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Premphase is covered by most Medicare and insurance plans.
With the Patient Assistance Program from Pfizer, you can receive your medication at no cost.

GoodRx coupon prices last updated on 02/15/26.
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