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Vumerity vs. Tecfidera

Vumerity (diroximel fumarate) is approved for treating relapsing forms of multiple sclerosis (MS) in adults. It's a type of disease-modifying therapy (DMT) that can help lower the number of MS relapses and slow MS from getting worse. Vumerity (diroximel fumarate) comes as a capsule that's taken by mouth twice a day. The dosage typically starts low and then is raised to the maintenance dose a week later. The most common side effects are stomach upset and flushing.

• Relapsing forms of multiple sclerosis (MS)

• Flushing (40%)
• Stomach pain (18%)
• Diarrhea (14%)
• Nausea (12%)

• Severe allergic reaction
• Flushing
• Risk of serious infections
• Low white blood cell counts
• Liver damage
• Serious stomach or gut problems

Dimethyl fumarate (Tecfidera) is used to treat adults with certain types of multiple sclerosis (MS), a condition that affects your nervous system. This medication is a disease-modifying therapy (DMT) that belongs to the drug class called fumaric acid derivatives. Dimethyl fumarate (Tecfidera) is available as a brand-name medication and a lower-cost generic. The capsules are taken by mouth twice per day. The most common side effects are stomach upset and flushing (e.g., facial warmth, redness, burning sensation).

• Relapsing forms of multiple sclerosis (MS)

• Flushing (40%)
• Stomach pain (18%)
• Diarrhea (14%)
• Nausea (12%)
• Vomiting (9%)
• Itchiness (8%)
• Rash (8%)

• Severe allergic reactions
• Serious infections
• Low white blood cell counts (lymphopenia)
• Liver damage
• Flushing
• Serious stomach and intestine problems