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Tecfidera vs. Vumerity

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Dimethyl fumarate

(Tecfidera)

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Vumerity

(diroximel fumarate)

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Summary for Tecfidera

Prescription only

Dimethyl fumarate (Tecfidera) is used to treat adults with certain types of multiple sclerosis (MS), a condition that affects your nervous system. This medication is a disease-modifying therapy (DMT) that belongs to the drug class called fumaric acid derivatives. Dimethyl fumarate (Tecfidera) is available as a brand-name medication and a lower-cost generic. The capsules are taken by mouth twice per day. The most common side effects are stomach upset and flushing (e.g., facial warmth, redness, burning sensation).

Indications for Tecfidera

Pros and Cons for Tecfidera

Pros

  • Works well to lessen MS relapses
  • Can take with or without food
  • Available as a lower-cost generic medication
  • No known interactions with other medications or supplements

Cons

Common Side Effects for Tecfidera

  • Flushing (40%)
  • Stomach pain (18%)
  • Diarrhea (14%)
  • Nausea (12%)
  • Vomiting (9%)
  • Itchiness (8%)
  • Rash (8%)

Warnings for Tecfidera

  • Severe allergic reactions
  • Serious infections
  • Low white blood cell counts (lymphopenia)
  • Liver damage
  • Flushing
  • Serious stomach and intestine problems

Summary for Vumerity

Prescription only

Vumerity, also known by its generic name dimethyl fumarate, is approved in adults for treating relapsing forms of multiple sclerosis (MS). It belongs to the drug class called fumaric acid derivatives. Vumerity (diroximel fumarate) is a capsule that's taken by mouth twice per day. The most common side effects are stomach upset and flushing (e.g., facial warmth, redness, burning sensation).

Indications for Vumerity

Pros and Cons for Vumerity

Pros

  • Lessens the number of relapses per year
  • Available in a "starter dose" bottle and "maintenance dose" bottle to help you keep track of how much medication to take
  • Few interactions with other medications

Cons

  • Have to take twice per day
  • Flushing is a common side effect
  • Shouldn't take the medication with high-fat and high-calorie meals

Common Side Effects for Vumerity

  • Flushing (40%)
  • Stomach pain (18%)
  • Diarrhea (14%)
  • Nausea (12%)

Warnings for Vumerity

  • Severe allergic reaction
  • Flushing
  • Risk for serious infections
  • Low white blood cell counts (lymphopenia)
  • Liver damage
  • Serious stomach and gut problems

Prices with our coupons for Tecfidera vs. Vumerity

Price Card Drug Icon
Dimethyl Fumarate1 bottle / 60 capsules of 240mg
$41.33$8,931.05
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Price Card Drug Icon
Vumerity1 bottle / Maintenance Dose of 231mg
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