Tecfidera vs. Vumerity for Multiple Sclerosis: Important Differences and Potential Risks.

Dimethyl fumarate

(Tecfidera)

Vumerity

(diroximel fumarate)

Summary for Tecfidera

Prescription only

Dimethyl fumarate (Tecfidera) is used to treat adults with certain types of multiple sclerosis (MS), a condition that affects your nervous system. This medication is a disease-modifying therapy (DMT) that belongs to the drug class called fumaric acid derivatives. Dimethyl fumarate (Tecfidera) is available as a brand-name medication and a lower-cost generic. The capsules are taken by mouth twice per day. The most common side effects are stomach upset and flushing (e.g., facial warmth, redness, burning sensation).

Indications for Tecfidera

Relapsing forms of multiple sclerosis (MS)

Pros and Cons for Tecfidera

Pros

Works well to lessen MS relapses
Can take with or without food
Available as a lower-cost generic medication
No known interactions with other medications or supplements

Cons

Need to take twice a day
Might need MRI scans to see whether the medication is working for you
Might need to have regular blood work done to make sure the medication isn't causing any liver problems
Can cause more bothersome stomach-related side effects than Vumerity (diroximel fumarate)

Common Side Effects for Tecfidera

Flushing (40%)
Stomach pain (18%)
Diarrhea (14%)
Nausea (12%)
Vomiting (9%)
Itchiness (8%)
Rash (8%)

Warnings for Tecfidera

Severe allergic reactions
Serious infections
Low white blood cell counts (lymphopenia)
Liver damage
Flushing
Serious stomach and intestine problems

Summary for Vumerity

Prescription only

Vumerity (diroximel fumarate) is approved for treating relapsing forms of multiple sclerosis (MS) in adults. It's a type of disease-modifying therapy (DMT) that can help lower the number of MS relapses and slow MS from getting worse. Vumerity (diroximel fumarate) comes as a capsule that's taken by mouth twice a day. The dosage typically starts low and then is raised to the maintenance dose a week later. The most common side effects are stomach upset and flushing.

Indications for Vumerity

Relapsing forms of multiple sclerosis (MS)

Pros and Cons for Vumerity

Pros

Taken by mouth
Can help lower the number of MS relapses per year
Might cause less stomach upset than dimethyl fumarate (Tecfidera)
Few drug interactions

Cons

Must take twice a day
Often causes flushing
Should avoid taking with high-fat and high-calorie meals
Can take a few months to see the full benefit of the medication

Common Side Effects for Vumerity

Flushing (40%)
Stomach pain (18%)
Diarrhea (14%)
Nausea (12%)

Warnings for Vumerity

Severe allergic reaction
Flushing
Risk of serious infections
Low white blood cell counts
Liver damage
Serious stomach or gut problems

Prices with our coupons for Tecfidera vs. Vumerity

Dimethyl Fumarate1 bottle / 60 capsules of 240mg

$39.34$8,936.76

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Vumerity1 bottle / Maintenance Dose of 231mg

$10,144.97-

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Tecfidera vs. Vumerity

Dimethyl fumarate

Vumerity

Summary for Tecfidera

Indications for Tecfidera

Pros and Cons for Tecfidera

Pros

Cons

Common Side Effects for Tecfidera

Warnings for Tecfidera

Summary for Vumerity

Indications for Vumerity

Pros and Cons for Vumerity

Pros

Cons

Common Side Effects for Vumerity

Warnings for Vumerity

Prices with our coupons for Tecfidera vs. Vumerity

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Dimethyl fumarate

Vumerity

Summary for Tecfidera

Indications for Tecfidera

Pros and Cons for Tecfidera

Pros

Cons

Common Side Effects for Tecfidera

Warnings for Tecfidera

Summary for Vumerity

Indications for Vumerity

Pros and Cons for Vumerity

Pros

Cons

Common Side Effects for Vumerity

Warnings for Vumerity