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Compare Trulicity vs. Mounjaro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Trulicity (dulaglutide)
    Mounjaro (tirzepatide)
  • Trulicity (dulaglutide)
    Mounjaro (tirzepatide)

  • Summary of Trulicity vs. Mounjaro

    Summary for GLP-1 agonist
    Prescription only

    Trulicity (dulaglutide) is a glucagon-like peptide-1 (GLP-1) agonist that helps control blood sugar in people 10 years and older with Type 2 diabetes. It's also approved to lower the risk of heart problems like heart attacks, strokes, and heart-related death in certain adults with Type 2 diabetes. The medication is injected under the skin once a week. Common side effects include nausea, vomiting, diarrhea, and stomach pain. When taken with certain diabetes medications like insulin, there's a higher risk of low blood sugar (hypoglycemia).

    Summary for GIP and GLP-1 agonist
    Prescription only

    Mounjaro (tirzepatide) is a prescription injection that's used together with diet and exercise to improve blood sugar control in adults with Type 2 diabetes. Mounjaro (tirzepatide) was approved by the FDA in May 2022 as the first one in a new class of medications called GIP and GLP-1 agonists. The dosage is convenient because it's injected under the skin once a week. Some common side effects of Mounjaro (tirzepatide) include nausea, vomiting, and diarrhea.

  • Indications of Trulicity vs. Mounjaro

    Indications for
    •Manage Type 2 diabetes in people 10 years and older, along with diet and exercise
    •Lower the risk of heart problems like heart attack, stroke, or death in adults with Type 2 diabetes who have heart disease or heart-related risk factors
    Indications for
    •Type 2 diabetes, in addition to diet and exercise

  • Pros and Cons of Trulicity vs. Mounjaro

    Pros and Const for GLP-1 agonist
    Pros
    •Works well at lowering A1C
    •Comes as a ready-to-use injectable pen
    •Only used once a week
    •Helps with weight loss
    Cons
    •Commonly causes nausea, vomiting, diarrhea, and stomach pain
    •Potential risk for thyroid tumors
    •Can cause problems in the pancreas, kidney, and gallbladder
    •Not recommended for people with stomach problems
    Pros and Const for GIP and GLP-1 agonist
    Pros
    •Given once weekly
    •Lowers A1C (average blood sugar over time) by up to 2.4% on average
    •Injections can be given with or without food
    •Comes as ready-to-use injectable pens with a pre-attached needle
    •Can use if you have liver or kidney problems
    Cons
    •Only available as an injection
    •Can cause unpleasant stomach side effects (e.g., nausea, vomiting, diarrhea)
    •Available as brand name only
    •Not approved for children
    •Might not be safe during pregnancy

  • Common Side Effects of Trulicity vs. Mounjaro

    Common Side Effects for
    •Nausea (12-21%)
    •Diarrhea (7-13%)
    •Vomiting (6-13%)
    •Stomach pain (7-9%)
    •Low appetite (5-9%)
    •Fatigue (4-6%)
    •Indigestion (3-6%)
    Common Side Effects for
    •Nausea (12-18%)
    •Diarrhea (12-17%)
    •Low appetite (5-11%)
    •Vomiting (5-9%)
    •Stomach upset or indigestion (5-8%)
    •Constipation (6-7%)
    •Stomach pain (5-6%)

  • Warnings of Trulicity vs. Mounjaro

    Common Side Effects for
    •Thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Low blood sugar when used with certain diabetes medications
    •Severe allergic reactions
    •Kidney damage
    •Severe stomach-related side effects
    •Worsening eye problems in people with diabetic retinopathy
    •Gallbladder problems
    •Breathing fluid into your lungs during anesthesia or deep sedation
    Common Side Effects for
    •Risk of thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Low blood sugar (hypoglycemia) when used with other diabetes medications
    •Allergic reactions
    •Stomach problems
    •Kidney damage
    •Eye problems related to high blood sugar (complications of diabetic retinopathy)
    •Gallbladder problems

  • Prices with our coupons for Trulicity vs. Mounjaro

    Learn more about Trulicity
    Learn more about Mounjaro

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