Gliptins

Gliptins or dipeptidyl peptidase-4 inhibitors are used to lower blood sugar levels to treat diabetes type 2. They work by increasing insulin and suppressing glucagon.

Why are gliptins prescribed?

Diabetes Type 2 (100%)

How are these percentages calculated?

Key takeaways

Gliptins (also called dipeptidyl peptidase-4, or DPP-4, inhibitors) are used to treat Type 2 diabetes. They work by blocking the enzyme dipeptidyl peptidase-4 (DPP-4), which helps increase natural insulin release and decrease the amount of glucose (sugar) your liver makes. These medications are available as oral tablets. Examples include sitagliptin (Januvia), saxagliptin (Onglyza), and linagliptin (Tradjenta). You can discuss with your healthcare team which option might be right for you.

Prices for popular Gliptins medications

Viewing 6 of 6 medications

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Tradjenta

as low as$278

Tradjenta (linagliptin) is used to help control blood sugar and treat type 2 diabetes. Tradjenta is slightly more popular than other gliptins. There are currently no generic alternatives to Tradjenta.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. The most common version of Tradjenta is covered by 85% of insurance plans at a co-pay of $35.00-$55.00, however, some pharmacy coupons or cash prices may be lower.

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saxagliptin

as low as$55

SAXAGLIPTIN treats type 2 diabetes. It works by increasing insulin levels in your body, which decreases your blood sugar (glucose). It also reduces the amount of sugar released into your blood. Changes to diet and exercise are often combined with this medication.

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Januvia

as low as$322

Januvia (sitagliptin) is used to treat type 2 diabetes. Januvia is a gliptin, which works by lowering blood sugar. The most common form of Januvia is a 100mg tablet. It is also avalible as a 50mg and 25mg tablet. There are currently no generic alternatives for Januvia. It is covered by some Medicare and insurance plans, but some pharmacy coupons, manufacturer programs, or cash prices may be lower.

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Nesina (alogliptin)

as low as$151

ALOGLIPTIN treats type 2 diabetes. It works by increasing insulin levels in your body, which decreases your blood sugar (glucose). It also reduces the amount of sugar released into your blood. Changes to diet and exercise are often combined with this medication.

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Zituvio (sitagliptin)

as low as$115

SITAGLIPTIN treats type 2 diabetes. It works by increasing insulin levels in your body, which decreases your blood sugar (glucose). It also reduces the amount of sugar released into your blood. Changes to diet and exercise are often combined with this medication.

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Brynovin

as low as$290

Brynovin is part of the Gliptins class and treats Diabetes Type 2. Gliptins or dipeptidyl peptidase-4 inhibitors are used to lower blood sugar levels to treat diabetes type 2. They work by increasing insulin and suppressing glucagon. Brynovin is only available as a brand name drug.

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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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