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Compare Saxagliptin vs. Januvia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Saxagliptin (Onglyza)
    Januvia (sitagliptin)
  • Saxagliptin (Onglyza)
    Januvia (sitagliptin)

  • Summary of Saxagliptin vs. Januvia

    Summary for DPP-4 inhibitor
    Prescription only

    Saxagliptin (Onglyza) is an add-on medication to exercise and a balanced, nutritious diet to improve blood sugar control in adults with Type 2 diabetes. It belongs to the drug class called dipeptidyl peptidase-4 (DPP-4) inhibitors. The saxagliptin (Onglyza) dosage is taken by mouth once daily. Possible side effects include certain infections and headaches. The brand name, Onglyza, is no longer available. But the lower-cost generic version is still available.

    Summary for DDP-4 inhibitor
    Prescription only

    Januvia (sitagliptin) is a prescription medication used along with a healthy diet and exercise to treat Type 2 diabetes. It belongs to the drug class dipeptidyl peptidase-4 (DPP-4) inhibitor, also known as gliptins. Januvia (sitagliptin) is taken by mouth, typically once daily. Most people don't experience many side effects from this medication, but possible ones include stuffy or runny nose, sore throat, and headache.

  • Indications of Saxagliptin vs. Januvia

    Indications for
    •Type 2 diabetes in adults
    Indications for
    •Type 2 diabetes in adults

  • Pros and Cons of Saxagliptin vs. Januvia

    Pros and Const for DPP-4 inhibitor
    Pros
    •Taken once daily (with or without food)
    •Less likely to cause weight gain (compared to some other diabetes medications)
    •Very low risk of causing hypoglycemia (low blood sugar) when it's taken by itself
    Cons
    •Doesn't lower A1C and blood sugar levels as well as other diabetes medications
    •Might raise risk of hospitalization due to heart failure in certain people
    •Not for treating Type 1 diabetes or diabetic ketoacidosis
    Pros and Const for DDP-4 inhibitor
    Pros
    •Only taken once a day
    •Can take with or without food
    •Not known to affect your body weight
    Cons
    •Can cause severe joint pain
    •Not a first choice option for people with Type 2 diabetes and heart problems
    •Might cause sudden kidney injury in people with kidney problems

  • Common Side Effects of Saxagliptin vs. Januvia

    Common Side Effects for
    •Upper respiratory tract infection (8%)
    •Urinary tract infection (UTI; 7%)
    •Headache (7%)
    Common Side Effects for
    •Runny nose, sore throat, and other symptoms of the common cold (5%)

  • Warnings of Saxagliptin vs. Januvia

    Common Side Effects for
    •Pancreas problems
    •Heart failure
    •Low blood sugar (hypoglycemia)
    •Joint pain
    •Large blisters
    •Risk of allergic reaction
    Common Side Effects for
    •Pancreas problems
    •Heart failure
    •Sudden kidney problems
    •Serious allergic reactions
    •Joint pain
    •Severe skin reactions

  • Prices with our coupons for Saxagliptin vs. Januvia

    Learn more about Saxagliptin
    Learn more about Januvia

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