Impoyz
Impoyz (clobetasol) is a very strong steroid cream that helps treat plaque psoriasis in adults. It's typically applied to the affected area(s) twice a day. Side effects aren't common but can include rash and changes to skin color at the application site.
What is Impoyz (clobetasol)?
What is Impoyz (clobetasol) used for?
Moderate-to-severe plaque psoriasis
How Impoyz (clobetasol) works
Impoyz (clobetasol) is a topical corticosteroid. When it’s used on the skin, it has a few actions.
It blocks inflammatory chemicals that cause redness, itching, and swelling. This helps lower skin inflammation.
It also slows down how fast new skin cells are made. This can help lessen the number of patches or scales from psoriasis.
It lessens the body's immune response. This can help with psoriasis since it's a skin problem that's caused by an overactive immune system.
Drug Facts
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What are the side effects of Impoyz (clobetasol)?
Common Side Effects
- Side effects aren't common. See Other Side Effects.
Other Side Effects
- Changes in skin color at the application site
- Skin thinning
- Rash
- Red or purple lines on skin (spider veins)
Source:Â DailyMed
The following side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Burning or stinging at the application site
Less common
Burning sensation of the skin
flushing or redness of the skin
itching, scaling, severe redness, soreness, or swelling of the skin
skin irritation
skin rash, encrusted, scaly and oozing
thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
Rare
Thinning, weakness, or wasting away of the skin
Incidence not known
Backache
blindness
blurred vision
burning, itching, and pain in hairy areas, or pus at the root of the hair
change in vision
facial hair growth in females
fractures
fruit-like breath odor
full or round face, neck, or trunk
headache
increased hunger
increased thirst
increased urination
irritability
loss of sexual desire or ability
menstrual irregularities
muscle wasting
redness and scaling around the mouth
stomach pain
sugar in the urine
sweating
tearing
thinning of the hair
troubled breathing
unexplained weight loss
unusual tiredness or weakness
vomiting
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Body aches or pain
changes in skin coloring
congestion
dryness of the throat
raised, dark red, wart-like spots on the skin, especially when used on the face
skin discomfort
stuffy or runny nose
tender, swollen glands in the neck
trouble swallowing
voice changes
Incidence not known
burning and itching of the skin with pinhead-sized red blisters
increased hair growth on the forehead, back, arms, and legs
lightening of normal skin color
lightening of treated areas of dark skin
reddish purple lines on the arms, face, legs, trunk, or groin
softening of the skin
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Pros and cons of Impoyz (clobetasol)
Pros
Applied directly to the affected area(s) of psoriasis
One of the most potent (strongest) topical steroids
Cons
Need to apply twice a day
Only meant for use up to 2 weeks at a time to prevent problems like skin thinning
Not approved for children under 18 years old
Pharmacist tips for Impoyz (clobetasol)
Ask your prescriber how long you should use Impoyz (clobetasol). Typically, you should only use it for no more than 2 weeks in a row, unless your prescriber says otherwise. Using Impoyz (clobetasol) every day for a long time can make side effects more likely to happen. This includes thin skin or more sensitive skin. Tell your prescriber if your psoriasis doesn't get any better after a couple weeks of use.
Only apply Impoyz (clobetasol) on skin that's not broken. Don't put it on wounds or damaged skin. More medication can get absorbed through damaged skin and cause more side effects.
Don't put Impoyz (clobetasol) in your mouth, eyes, nose, or ears. You also shouldn't use the medication on your face, armpits, groin, or into the vagina. These areas are all sensitive and can get irritated easily. Impoyz (clobetasol) also isn't meant to be used on the scalp. If you need treatment on these areas, talk to your prescriber about your options.
Gently and completely rub Impoyz (clobetasol) into the affected area(s) of your skin.
Wash your hands after using Impoyz (clobetasol). This helps get rid of any medication that's left on your hands before touching other things. If it accidentally gets in your eyes, rinse your eyes with water and let your care team know if irritation doesn't go away.
Don't cover the treated area with a bandage unless directed by your prescriber. Covering the area tightly can make more Impoyz (clobetasol) get absorbed through the skin. This can raise your risk of more side effects.
If you've been using Impoyz (clobetasol) for a few weeks and need to stop, talk to your prescriber. They might tell you to apply less over time before you stop. This can help lower your risk of topical steroid withdrawal.
Frequently asked questions about Impoyz (clobetasol)
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What are the risks and warnings for Impoyz (clobetasol)?
Impoyz (clobetasol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
More skin reactions with longer use and coverings
Risk factors: Using a higher dose of Impoyz (clobetasol) over a longer period of time | Covering applied area with a bandage
Regularly using Impoyz (clobetasol) longer than recommended can raise your risk of more skin reactions. Your risk is also higher if you cover the treated area with a tight bandage.
These skin reactions can include skin thinning, burning, itching, irritation, and dry skin. It can also include stretch marks, inflamed hair follicles, or changes in skin color. Some of these skin reactions can be permanent.
To prevent severe skin reactions, use the smallest amount of Impoyz (clobetasol) needed for the shortest period of time possible. Let your care team know right away if you notice any new or worsening skin problems. Your care team can check to see what's going on.
Changes in stress hormone levels
Risk factors: Using high potency topical steroids | Using Impoyz (clobetasol) regularly for a longer time than recommended | Applying onto damaged skin | Covering the treated area with a bandage | Using more than one steroid medication at the same time | Liver failure
Impoyz (clobetasol) is a strong steroid that works like your body's natural stress hormone, cortisol. Using it too often, for too long, or on large skin areas can affect your cortisol levels.
Sometimes, your cortisol levels could get too high. This could cause symptoms of Cushing's syndrome and high blood sugar. Other times, it can cause low cortisol levels, which can make you feel weak or unwell.
To stay safe, use the lowest Impoyz (clobetasol) dose. Use it for no more than 2 weeks at a time for most formulations or for no more than 4 weeks at a time for the shampoo, unless your prescriber says it's okay. If you need to use Impoyz (clobetasol) longer or over a large area, talk to your prescriber about how to use it safely.
Topical steroid withdrawal
Topical steroid withdrawal (TSW) is possible with Impoyz (clobetasol). This can happen if you stop using the medication suddenly after regular use. Some symptoms of TSW include itchy, burning, or flaky skin. You might also become sensitive to water, clothing, movement, and temperature.
If this happens, talk to your prescriber. They can suggest ways to help with this problem. Don't suddenly stop using Impoyz (clobetasol) without talking to your prescriber first.
Allergic skin reaction
Skin irritation that doesn't go away can be an early sign of an allergic skin reaction to Impoyz (clobetasol). Tell your prescriber if your skin condition doesn't get better or worsens.
Treat any skin infections appropriately
Tell your care team if you get a skin infection while using Impoyz (clobetasol). Look for signs of a skin infection, like redness, pain, swelling, or pus.
Topical steroids like Impoyz (clobetasol) can sometimes make skin infections worse or take longer to heal. So, it's important to treat the skin infection with the right medication, like an antifungal or antibacterial. If the infection doesn't get better with treatment, tell your care team. You might have to stop using Impoyz (clobetasol) until the infection goes away.
Impoyz (clobetasol) dosage forms
Typical dosing for Impoyz (clobetasol)
Apply a thin layer of cream to the affected area(s) twice daily for up to 2 weeks at a time. Don't use more than 50 grams per week.
Interactions between Impoyz (clobetasol) and other drugs
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Bemiparin
- Lutetium Lu 177 Dotatate
- Macimorelin
- Nadroparin
- Sargramostim
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Auranofin
How much does Impoyz (clobetasol) cost?
What are alternatives to Impoyz (clobetasol)?
Moderate-to-severe plaque psoriasis
Skin inflammation disorders, including psoriasis, eczema, and seborrheic dermatitis
Inflammatory skin conditions - cream and ointment only
Plaque psoriasis - lotion and foam only
What is the latest news about Impoyz (clobetasol)?
Impoyz (clobetasol) images
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