Key takeaways
Zestoretic (lisinopril/hydrochlorothiazide) and metoprolol tartrate (Lopressor) are both used to treat high blood pressure, but they work in different ways and have different uses. Zestoretic is a combination of an ACE inhibitor and a diuretic, which helps relax blood vessels and remove extra water and electrolytes from your body. It's typically taken once daily. Metoprolol tartrate, on the other hand, is a beta blocker that slows down your heart rate and is usually taken twice daily. Besides high blood pressure, metoprolol tartrate is also used to treat chest pain and lower the risk of death after a heart attack. Zestoretic is not safe for use during pregnancy, while metoprolol tartrate can be an option for breastfeeding mothers. Common side effects of Zestoretic include dizziness and cough, whereas metoprolol tartrate can cause tiredness and dizziness. Both medications are available in generic forms, making them more affordable options.
