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Compare Vyepti vs. Emgality

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Vyepti (eptinezumab)
    Emgality (galcanezumab)
  • Vyepti (eptinezumab)
    Emgality (galcanezumab)

  • Summary of Vyepti vs. Emgality

    Summary for CGRP receptor blocker
    Prescription only

    Vyepti (eptinezumab or eptinezumab-jjmr) is a medication that's used to prevent migraines in adults. The dose is given as an infusion through the veins at a provider's office or clinic every 3 months. Side effects aren't common, but they can include common cold symptoms, itching, and flushing. Vyepti (eptinezumab) is only available as a brand name.

    Summary for CGRP antagonist
    Prescription only

    Emgality (galcanezumab or galcanezumab-gnlm) is an injectable medication that can help prevent migraine attacks in adults. It can also help treat cluster headaches in adults. This medication is a monoclonal antibody that works as a CGRP antagonist. It blocks the CGRP protein in the brain that can cause migraine and headache pain. Emgality (galcanezumab) comes as a prefilled pen and syringe. You inject one dose of the medication under the skin monthly. Some common side effects include pain, itching, and redness at the injection site.

  • Indications of Vyepti vs. Emgality

    Indications for
    •Prevention of migraines in adults
    Indications for
    •Prevention of migraines in adults
    •Treatment of episodic (occasional) cluster headaches in adults

  • Pros and Cons of Vyepti vs. Emgality

    Pros and Const for CGRP receptor blocker
    Pros
    •Works well to lower the number of migraines you get
    •Taken only every 3 months
    •Few side effects
    Cons
    •Given as an infusion through the veins (IV)
    •Needs to be given by a healthcare provider
    •Hasn't been studied well enough in children or in older adults, so it's not completely known how well the medication works for them
    Pros and Const for CGRP antagonist
    Pros
    •Only needs to be given once a month
    •Good option for people who have a hard time taking medications by mouth
    •Generally well tolerated
    Cons
    •Not a good option for people who don't like needles
    •Need to store in a refrigerator
    •Not known if the medication works well or is safe in children, during pregnancy, or while breastfeeding

  • Common Side Effects of Vyepti vs. Emgality

    Common Side Effects for
    •Common cold symptoms (6-8%)
    Common Side Effects for
    •Pain, itching, warmth, and other injection site reactions (18%)

  • Warnings of Vyepti vs. Emgality

    Common Side Effects for
    •Allergic reactions
    Common Side Effects for
    •Serious allergic reactions
    •High blood pressure
    •Raynaud's phenomenon

  • Prices with our coupons for Vyepti vs. Emgality

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    Learn more about Emgality

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