Key takeaways
Sumatriptan (Imitrex) and almotriptan (Axert) are both triptans used to treat migraines, but they have some differences. Sumatriptan is available in various forms, including tablets, injections, and nasal sprays, while almotriptan is only available as a tablet. Sumatriptan can be taken by adults and is available as a lower-cost generic, whereas almotriptan can be used by both adults and children aged 12 and older. Sumatriptan starts working within about 2 hours, while Almotriptan typically starts working within 1 to 3 hours. Both medications can cause side effects like dizziness and fatigue, as well as serious side effects like high blood pressure and heart problems. Almotriptan can cause allergic reactions those allergic to sulfa medications. Both medications should not be used more than 9 days per month to avoid worsening headaches.
