Ubrelvy vs. Sumatriptan for Migraine: Important Differences and Potential Risks.

Ubrelvy

(ubrogepant)

Sumatriptan

(Imitrex)

Summary for Ubrelvy

Prescription only

Ubrelvy (ubrogepant) is a migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It can treat sudden migraine attacks in adults. Ubrelvy (ubrogepant) is a tablet you take by mouth. You take one dose when you feel a migraine starting. If needed, you can take a second dose at least 2 hours later. Your dose depends if Ubrelvy (ubrogepant) interacts with the other medications you take. Side effects include nausea and tiredness.

Indications for Ubrelvy

Treatment of migraine attacks with or without aura in adults

Pros and Cons for Ubrelvy

Pros

A tablet that's taken by mouth
Helps treat sudden migraine attacks
Good option when triptans like sumatriptan (Imitrex) haven't worked well

Cons

Takes 1 to 2 hours to start working
Not for preventing migraines
Can interact with other medications, like verapamil and phenobarbital

Common Side Effects for Ubrelvy

Nausea (up to 4%)
Sleepiness (up to 3%)
Dry mouth (up to 2%)

Warnings for Ubrelvy

Allergic reactions
High blood pressure
Raynaud's phenomenon

Summary for Sumatriptan

Prescription only

Sumatriptan (Imitrex) is used to treat migraines with or without aura in adults. The medication is typically taken as a single dose for your migraine. But, it's possible that you can take it again 2 hours after the first dose if your migraine doesn't go away. Side effects of sumatriptan (Imitrex) include tingling or numbness of fingers or toes, feeling too warm or too cold, and fatigue. It can interact with antidepressants and other similar migraine medications. Sumatriptan (Imitrex) is available as a lower-cost generic tablet.

Indications for Sumatriptan

Treatment of migraine attacks with or without aura in adults

Pros and Cons for Sumatriptan

Pros

First-choice option for treating migraines
Can take with commonly used over-the-counter pain relievers like acetaminophen (Tylenol)
Can start relieving migraine headaches within 30 minutes to 2 hours
Available as a lower-cost generic

Cons

Can't use to prevent migraines
Must wait at least 2 hours after the first dose to take a second dose, if needed
Your migraines can get worse if you use this medication too often.
Unknown if it's safe or if it works well in children

Common Side Effects for Sumatriptan

Tingling or numbness of fingers or toes (3-5%)
Feeling too warm or too cold (2-3%)
Fatigue (2-3%)

Warnings for Sumatriptan

Heart problems and high blood pressure
Stroke or other brain injury
Extreme narrowing of blood vessels
Serotonin syndrome
Allergic reactions
Seizures

Prices with our coupons for Ubrelvy vs. Sumatriptan

Ubrelvy10 tablets / 100mg

$1,103.13$1,423.56

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Sumatriptan1 dose pack / 9 tablets of 100mg

$14.40$78.46

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Ubrelvy vs. Sumatriptan

Ubrelvy

Sumatriptan

Summary for Ubrelvy

Indications for Ubrelvy

Pros and Cons for Ubrelvy

Pros

Cons

Common Side Effects for Ubrelvy

Warnings for Ubrelvy

Summary for Sumatriptan

Indications for Sumatriptan

Pros and Cons for Sumatriptan

Pros

Cons

Common Side Effects for Sumatriptan

Warnings for Sumatriptan

Prices with our coupons for Ubrelvy vs. Sumatriptan

Compare other Migraine drugs

Browse medications by letter

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Ubrelvy

Sumatriptan

Summary for Ubrelvy

Indications for Ubrelvy

Pros and Cons for Ubrelvy

Pros

Cons

Common Side Effects for Ubrelvy

Warnings for Ubrelvy

Summary for Sumatriptan

Indications for Sumatriptan

Pros and Cons for Sumatriptan

Pros

Cons

Common Side Effects for Sumatriptan

Warnings for Sumatriptan