Key takeaways
Fesoterodine (Toviaz) and solifenacin (Vesicare) are both medications used to treat overactive bladder (OAB), but they have some differences. Fesoterodine (Toviaz) is an anticholinergic urinary antispasmodic that also treats neurogenic detrusor overactivity (NDO) in children, while solifenacin (Vesicare) is an anticholinergic and antimuscarinic that can be used for incontinence in children due to neurological conditions. Fesoterodine (Toviaz) is available as a generic, whereas solifenacin (Vesicare) has a generic form for tablets but not for its liquid version. Both medications are taken once a day, but fesoterodine (Toviaz) is an extended-release tablet, and solifenacin (Vesicare) can be taken as a tablet or liquid. Common side effects for both include dry mouth and constipation, but solifenacin (Vesicare) tends to have milder side effects overall. Additionally, solifenacin (Vesicare) can cause rare but serious heart rhythm problems, which is not noted for fesoterodine (Toviaz).
