Key takeaways
Silodosin (Rapaflo) and Alfuzosin (Uroxatral) are both alpha-1 blockers used to treat symptoms of benign prostatic hyperplasia (BPH). Silodosin is available as a capsule, while Alfuzosin comes in an extended-release tablet form. You take Silodosin once daily with a meal, and it can cause side effects like retrograde ejaculation and dizziness. Alfuzosin is also taken once daily after the same meal each day and can cause dizziness and headaches. Unlike Silodosin, Alfuzosin should not be crushed or chewed because it is an extended-release medication. Both medications can lower your blood pressure, but Alfuzosin has a specific warning about causing a painful erection called priapism, which is rare. Additionally, Silodosin is not recommended for people with severe kidney or liver problems, while Alfuzosin should be avoided in those with moderate to severe liver issues. Both medications are available in generic forms, making them more affordable options.
