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Qulipta vs. Aimovig

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Atogepant (Qulipta) and erenumab (Aimovig) are both medications used to prevent migraines in adults, and they belong to the class of calcitonin gene-related peptide (CGRP) receptor blockers. However, they differ in several ways. Atogepant is taken orally once a day, while erenumab is administered as an injection under the skin once a month. Both medications are available only as brand-name products, with no generic versions currently available. Common side effects of atogepant include nausea, constipation, and sleepiness, whereas erenumab may cause pain at the injection site, constipation, and high blood pressure. Additionally, atogepant can interact with many medications, such as rifampin (Rifadin) and clarithromycin. It's important to discuss with a healthcare professional which medication might be best for you based on your needs and medical history.

Qulipta

(atogepant)

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Aimovig

(erenumab)

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Summary for Qulipta

Prescription only

Qulipta (atogepant) is a medication that's used to prevent migraines in adults. The specific dosing will depend on how many migraines you have per month, but the medication is typically taken once daily. Qulipta (atogepant) is currently brand only; it isn't available as a lower-cost generic yet. Side effects include nausea, constipation, and sleepiness.

Indications for Qulipta

  • Prevention of migraines in adults

Pros and Cons for Qulipta

Pros

  • Taken once per day
  • Can take with or without food
  • Can use if you have mild-to-moderate liver problems

Cons

  • Not used for treating a migraine attack
  • Unknown whether it's safe or works well in children
  • Hasn't been studied in pregnant women

Common Side Effects for Qulipta

  • Nausea (5-9%)
  • Constipation (6-8%)
  • Fatigue or sleepiness (4-5%)

Warnings for Qulipta

  • Allergic reactions

Summary for Aimovig

Prescription only

Aimovig (erenumab or erenumab-aooe) is a migraine medication called a CGRP antagonist. It helps prevent migraines in adults. Aimovig (erenumab) comes as an autoinjector and prefilled syringe. You inject each dose under the skin in the thigh or stomach once a month. Side effects can include pain, swelling, or redness where you injected the medication.

Indications for Aimovig

Pros and Cons for Aimovig

Pros

  • Taken only once a month to help prevent migraines
  • Available as a prefilled syringe and a prefilled autoinjector

Cons

  • Must give as an injection under the skin
  • Not approved for children

Common Side Effects for Aimovig

  • Pain, swelling, or redness at the injection site (up to 6%)
  • Constipation (up to 3%)

Warnings for Aimovig

  • Allergic reactions
  • Constipation with serious complications
  • High blood pressure
  • Raynaud's phenomenon

Prices with our coupons for Qulipta vs. Aimovig

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Qulipta30 tablets / 60mg
$1,110.89$1,400.02
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Aimovig1 sureclick / 140mg/ml
$299.00$924.99
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