Key takeaways
Gabapentin (Neurontin) and Phenytoin (Dilantin) are both antiepileptic medications, but they have different uses and side effects. Gabapentin is used to treat certain seizures and nerve pain, while Phenytoin is used to treat tonic-clonic and psychomotor seizures, as well as seizures during and after brain surgery. Gabapentin is available in generic form and can be taken as a tablet, capsule, or liquid, typically three times a day. Phenytoin is also available in generic form and comes as a capsule, chewable tablet, or liquid, with dosing that can be adjusted based on blood levels. Gabapentin can cause dizziness and sleepiness, and it has a risk of misuse, and is a controlled substance in some states. Phenytoin, on the other hand, has many drug interactions and can cause liver damage as a serious side effect. Additionally, Phenytoin requires regular blood tests to monitor levels and can cause changes in appearance, such as unwanted hair growth and gum enlargement. Both medications can increase the risk of suicidal thoughts or behavior.
