Kerendia vs. Spironolactone for Heart Failure: Important Differences and Potential Risks.

Kerendia

(finerenone)

Spironolactone

(Aldactone)

Summary for Kerendia

Prescription only

Kerendia (finerenone) is a mineralocorticoid receptor antagonist used to lower the risk of serious kidney and heart problems. It's approved for adults with chronic kidney disease (CKD) caused by Type 2 diabetes and for certain adults with heart failure. You take the medication by mouth once a day, with or without food. Common side effects include high potassium levels, low blood pressure, and low sodium levels.

Indications for Kerendia

Lowers the risk of serious problems in adults with chronic kidney disease (CKD) caused by Type 2 diabetes
Lowers the risk of serious problems in certain adults with heart failure

Pros and Cons for Kerendia

Pros

Protects your kidneys and lowers heart risks
Taken by mouth once per day
Can be taken with or without food

Cons

Won't be able to "feel" the medication working
Can raise blood potassium levels
Requires regular blood test to check potassium levels and kidney function

Common Side Effects for Kerendia

High blood potassium levels (14%)

Warnings for Kerendia

High potassium levels
Worsening kidney function (people with heart failure)

Summary for Spironolactone

Prescription only

Spironolactone (Aldactone) is a type of potassium-sparing diuretic (water pill). It's used to treat heart failure, high blood pressure, and swelling from kidney or liver problems in adults. Because it blocks aldosterone (a hormone that affects sodium and potassium levels), spironolactone (Aldactone) can also treat conditions where there's too much aldosterone. Spironolactone (Aldactone) is taken by mouth, generally once or a few times a day, depending on your condition. Some common side effects of this medication include breast tenderness (males and females) and loss of libido (in males).

Indications for Spironolactone

Heart failure
High blood pressure
Swelling due to liver damage (cirrhosis)
Swelling due to nephrotic syndrome (a rare kidney condition) - tablets only
Primary aldosteronism (a hormone imbalance) - tablets only

Pros and Cons for Spironolactone

Pros

Taken by mouth
Oral suspension available for adults who've difficulty swallowing tablets
Lower-cost generics available

Cons

Can make you urinate more often
Need to get blood tests regularly to check your electrolytes and kidney health
Can cause breast growth and lower sex drive in males

Common Side Effects for Spironolactone

Dizziness
Headache
Sleepiness
Nausea
Vomiting
Diarrhea
Stomach cramps
Enlargement of male breasts
Breast pain
Lower sex drive
Sexual dysfunction
Irregular or lack of menstrual periods
Leg cramps
Higher potassium levels
Lower sodium levels

Warnings for Spironolactone

High blood potassium levels
Low blood pressure and kidney problems
Abnormal electrolyte levels
Breast pain or swelling

Prices with our coupons for Kerendia vs. Spironolactone

Kerendia30 tablets / 10mg

$641.45$856.21

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Spironolactone30 tablets / 25mg

$8.89$17.99

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Kerendia vs. Spironolactone

Kerendia

Spironolactone

Summary for Kerendia

Indications for Kerendia

Pros and Cons for Kerendia

Pros

Cons

Common Side Effects for Kerendia

Warnings for Kerendia

Summary for Spironolactone

Indications for Spironolactone

Pros and Cons for Spironolactone

Pros

Cons

Common Side Effects for Spironolactone

Warnings for Spironolactone

Prices with our coupons for Kerendia vs. Spironolactone

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Kerendia

Spironolactone

Summary for Kerendia

Indications for Kerendia

Pros and Cons for Kerendia

Pros

Cons

Common Side Effects for Kerendia

Warnings for Kerendia

Summary for Spironolactone

Indications for Spironolactone

Pros and Cons for Spironolactone

Pros

Cons

Common Side Effects for Spironolactone

Warnings for Spironolactone