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Compare Kerendia vs. Spironolactone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Kerendia (finerenone)
    Spironolactone (Aldactone)
  • Kerendia (finerenone)
    Spironolactone (Aldactone)

  • Summary of Kerendia vs. Spironolactone

    Summary for Mineralocorticoid receptor antagonist
    Prescription only

    Kerendia (finerenone) is a mineralocorticoid receptor antagonist used to lower the risk of serious kidney and heart problems. It's approved for adults with chronic kidney disease (CKD) caused by Type 2 diabetes and for certain adults with heart failure. You take the medication by mouth once a day, with or without food. Common side effects include high potassium levels, low blood pressure, and low sodium levels.

    Summary for Potassium sparing diuretic
    Prescription only

    Spironolactone (Aldactone) is a type of potassium-sparing diuretic (water pill). It's used to treat heart failure, high blood pressure, and swelling from kidney or liver problems in adults. Because it blocks aldosterone (a hormone that affects sodium and potassium levels), spironolactone (Aldactone) can also treat conditions where there's too much aldosterone. Spironolactone (Aldactone) is taken by mouth, generally once or a few times a day, depending on your condition. Some common side effects of this medication include breast tenderness (males and females) and loss of libido (in males).

  • Indications of Kerendia vs. Spironolactone

    Indications for
    •Lowers the risk of serious problems in adults with chronic kidney disease (CKD) caused by Type 2 diabetes
    •Lowers the risk of serious problems in certain adults with heart failure
    Indications for
    •Heart failure
    •High blood pressure
    •Swelling due to liver damage (cirrhosis)
    •Swelling due to nephrotic syndrome (a rare kidney condition) - tablets only
    •Primary aldosteronism (a hormone imbalance) - tablets only

  • Pros and Cons of Kerendia vs. Spironolactone

    Pros and Const for Mineralocorticoid receptor antagonist
    Pros
    •Protects your kidneys and lowers heart risks
    •Taken by mouth once per day
    •Can be taken with or without food
    Cons
    •Won't be able to "feel" the medication working
    •Can raise blood potassium levels
    •Requires regular blood test to check potassium levels and kidney function
    Pros and Const for Potassium sparing diuretic
    Pros
    •Taken by mouth
    •Oral suspension available for adults who've difficulty swallowing tablets
    •Lower-cost generics available
    Cons
    •Can make you urinate more often
    •Need to get blood tests regularly to check your electrolytes and kidney health
    •Can cause breast growth and lower sex drive in males

  • Common Side Effects of Kerendia vs. Spironolactone

    Common Side Effects for
    •High blood potassium levels (14%)
    Common Side Effects for
    •Dizziness
    •Headache
    •Sleepiness
    •Nausea
    •Vomiting
    •Diarrhea
    •Stomach cramps
    •Enlargement of male breasts
    •Breast pain
    •Lower sex drive
    •Sexual dysfunction
    •Irregular or lack of menstrual periods
    •Leg cramps
    •Higher potassium levels
    •Lower sodium levels

  • Warnings of Kerendia vs. Spironolactone

    Common Side Effects for
    •High potassium levels
    •Worsening kidney function (people with heart failure)
    Common Side Effects for
    •High blood potassium levels
    •Low blood pressure and kidney problems
    •Abnormal electrolyte levels
    •Breast pain or swelling

  • Prices with our coupons for Kerendia vs. Spironolactone

    Learn more about Kerendia
    Learn more about Spironolactone

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