Glyxambi vs. Ozempic for Diabetes Type 2: Important Differences and Potential Risks.

Glyxambi

(empagliflozin / linagliptin)

Ozempic

(semaglutide)

Summary for Glyxambi

Prescription only

Glyxambi (empagliflozin / linagliptin) is a medication that helps manage blood sugar in adults with Type 2 diabetes. It works best when used with a balanced diet and exercise. It can also help lower the risk of heart-related death in adults with both Type 2 diabetes and heart disease. Glyxambi combines two diabetes medications into one tablet. They belong to the sodium-glucose co-transporter 2 (SGLT2) inhibitor and a dipeptidyl peptidase-4 (DPP-4) inhibitor drug classes. Glyxambi is taken by mouth once every morning. Side effects can include urinary tract infections and upper respiratory tract infections.

Indications for Glyxambi

Type 2 diabetes in adults
Lowering the risk of death due to heart problems in adults with Type 2 diabetes and heart disease

Pros and Cons for Glyxambi

Pros

Combines two diabetes medications into one pill
Taken once a day in the morning, with or without food
Less likely to cause low blood sugar when taken by itself

Cons

Might cause more urination
Can raise the risk of urinary tract infections or genital yeast infections
Not approved for people with Type 1 diabetes

Common Side Effects for Glyxambi

Urinary tract infection (11-13%)
Upper respiratory tract infection (7%)
Cold symptoms (6-7%)

Warnings for Glyxambi

Inflammation of the pancreas (pancreatitis)
Ketoacidosis (too much acid in the blood)
Low fluids in the body (leading to low blood pressure or dehydration)
Low blood sugar (hypoglycemia) when used with certain other diabetes medications
Genital and urinary tract infections
Leg and foot amputations
Serious allergic reactions
Severe skin reaction
Severe joint pain
Risk of heart failure

Summary for Ozempic

Prescription only

Ozempic (semaglutide) is a GLP-1 agonist used with diet and exercise to help adults manage Type 2 diabetes. It can also lower the risk of heart attack, stroke, and heart-related death in some people with Type 2 diabetes. It comes as a once-weekly injection under the skin and as a tablet taken by mouth once a day. The injection is also approved to help slow worsening kidney problems in people with Type 2 diabetes and chronic kidney disease (CKD). Common side effects include nausea, vomiting, and diarrhea.

Indications for Ozempic

Injection:

Type 2 diabetes
Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes and heart disease
Lower the risk of worsening kidney problems and heart-related death in adults with Type 2 diabetes and chronic kidney disease (CKD)

Tablets:

Type 2 diabetes
Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes at high risk for these events

Pros and Cons for Ozempic

Pros

Only given once per week
Might help you lose weight
Helps lower the risk of heart problems and kidney problems in people with type 2 diabetes
Available as an injection and an oral tablet

Cons

Commonly causes nausea, vomiting, and diarrhea
Risk of low blood sugar if taken with certain diabetes medications
Can't be used for Type 1 diabetes
Interacts with medications taken by mouth

Common Side Effects for Ozempic

Nausea (16-20%)
Diarrhea (9%)
Vomiting (5-9%)
Stomach pain (6-7%)
Constipation (3-5%)

Note: Side effects listed above are for Ozempic (semaglutide) injection

Warnings for Ozempic

Risk of thyroid tumors
Inflammation of the pancreas (pancreatitis)
Eye problems
Low blood sugar (hypoglycemia) when taken with certain diabetes medications
Kidney damage
Severe stomach problems
Severe allergic reactions
Gallbladder problems
Lung problems during anesthesia or deep sedation

Prices with our coupons for Glyxambi vs. Ozempic

Glyxambi30 tablets / 25mg/5mg

$352.68$426.99

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Ozempic30 tablets / 1.5mg

$149.00$1,209.71

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Glyxambi vs. Ozempic

Glyxambi

Ozempic

Summary for Glyxambi

Indications for Glyxambi

Pros and Cons for Glyxambi

Pros

Cons

Common Side Effects for Glyxambi

Warnings for Glyxambi

Summary for Ozempic

Indications for Ozempic

Pros and Cons for Ozempic

Pros

Cons

Common Side Effects for Ozempic

Warnings for Ozempic

Prices with our coupons for Glyxambi vs. Ozempic

Compare other Diabetes Type 2 drugs

Browse medications by letter

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Glyxambi

Ozempic

Summary for Glyxambi

Indications for Glyxambi

Pros and Cons for Glyxambi

Pros

Cons

Common Side Effects for Glyxambi

Warnings for Glyxambi

Summary for Ozempic

Indications for Ozempic

Pros and Cons for Ozempic

Pros

Cons

Common Side Effects for Ozempic

Warnings for Ozempic