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Compare Glyxambi vs. Ozempic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Glyxambi (empagliflozin / linagliptin)
    Ozempic (semaglutide)
  • Glyxambi (empagliflozin / linagliptin)
    Ozempic (semaglutide)

  • Summary of Glyxambi vs. Ozempic

    Summary for SGLT2 inhibitor / DPP-4 inhibitor
    Prescription only

    Glyxambi (empagliflozin / linagliptin) is used to manage blood sugar levels in adults with Type 2 diabetes. It's a combination of 2 medications: empagliflozin (a sodium-glucose co-transporter 2 (SGLT2) inhibitor) and linagliptin (a dipeptidyl peptidase-4 (DPP-4) inhibitor). It lowers blood sugar by getting rid of extra sugar through your urine and helping your body make more insulin. Glyxambi (empagliflozin / linagliptin) is taken by mouth once daily. Some common side effects include urinary tract infections and upper respiratory tract infections.

    Summary for GLP-1 agonist
    Prescription only

    Ozempic (semaglutide) is a GLP-1 agonist used with diet and exercise to help adults manage Type 2 diabetes. It can also lower the risk of heart attack, stroke, and heart-related death in some people with Type 2 diabetes. It comes as a once-weekly injection under the skin and as a tablet taken by mouth once a day. The injection is also approved to help slow worsening kidney problems in people with Type 2 diabetes and chronic kidney disease (CKD). Common side effects include nausea, vomiting, and diarrhea.

  • Indications of Glyxambi vs. Ozempic

    Indications for
    •Type 2 diabetes in adults (when taken along with nutritious diet and regular exercise)
    •Lowers risk of death from heart problems in adults with Type 2 diabetes and heart disease
    Indications for

    Injection:

    •Type 2 diabetes
    •Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes and heart disease
    •Lower the risk of worsening kidney problems and heart-related death in adults with Type 2 diabetes and chronic kidney disease (CKD)

    Tablets:

    •Type 2 diabetes
    •Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes at high risk for these events

  • Pros and Cons of Glyxambi vs. Ozempic

    Pros and Const for SGLT2 inhibitor / DPP-4 inhibitor
    Pros
    •Combines two medications into one pill for convenience
    •Can lower the risk of death from heart attack or stroke in people with Type 2 diabetes and heart disease
    •Only taken once a day in the morning with or without food
    •Not likely to cause weight gain
    Cons
    •Not safe for use in people on dialysis
    •Not approved for people with Type 1 diabetes
    •Might cause you to urinate more often
    •Might cause urinary tract infections or genital yeast infections
    Pros and Const for GLP-1 agonist
    Pros
    •Only given once per week
    •Might help you lose weight
    •Helps lower the risk of heart problems and kidney problems in people with type 2 diabetes
    •Available as an injection and an oral tablet
    Cons
    •Commonly causes nausea, vomiting, and diarrhea
    •Risk of low blood sugar if taken with certain diabetes medications
    •Can't be used for Type 1 diabetes
    •Interacts with medications taken by mouth

  • Common Side Effects of Glyxambi vs. Ozempic

    Common Side Effects for
    •Urinary tract infection (11-13%)
    •Upper respiratory tract infection (7%)
    Common Side Effects for
    •Nausea (16-20%)
    •Diarrhea (9%)
    •Vomiting (5-9%)
    •Stomach pain (6-7%)
    •Constipation (3-5%)

    Note: Side effects listed above are for Ozempic (semaglutide) injection

  • Warnings of Glyxambi vs. Ozempic

    Common Side Effects for
    •Pancreas problems
    •Ketoacidosis (too much acid in the blood)
    •Low fluids in the body (leading to low blood pressure or dehydration, or kidney problems)
    •Low blood sugar with other diabetes medications
    •Genital and urinary tract infections
    •Serious allergic or skin reactions
    •Joint pain
    •Leg and foot amputations
    •Heart failure
    Common Side Effects for
    •Risk of thyroid tumors
    •Inflammation of the pancreas (pancreatitis)
    •Eye problems
    •Low blood sugar (hypoglycemia) when taken with certain diabetes medications
    •Kidney damage
    •Severe stomach problems
    •Severe allergic reactions
    •Gallbladder problems
    •Lung problems during anesthesia or deep sedation

  • Prices with our coupons for Glyxambi vs. Ozempic

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