Key takeaways
Glipizide/metformin (generic) and Novolin N (insulin NPH) are both used to manage diabetes, but they have several differences between them. Glipizide/metformin is a combination medication, used to treat people with type 2 diabetes, that includes glipizide and metformin. It helps lower blood sugar by telling your pancreas to release insulin and reducing sugar production and absorption in the body. Novolin N is an intermediate-acting insulin used to treat both type 1 and type 2 diabetes. It helps your body absorb and store sugar and fat from your bloodstream after meals. While glipizide/metformin must be taken with meals to avoid low blood sugar, Novolin N requires careful blood sugar monitoring and can be used with or without other insulins. Novolin N is available over the counter, whereas glipizide/metformin requires a prescription. Additionally, Novolin N can be used in people with liver or kidney problems, unlike glipizide/metformin, which may not be safe for those with severe kidney issues.
