Key takeaways
Darifenacin ER (formerly brranded as Enablex) and oxybutynin ER (formerly branded as Ditropan and Ditropan XL) are both used to treat overactive bladder (OAB) but have some differences. Darifenacin is taken once a day and is known for having fewer side effects compared to oxybutynin, making it a better option for some people. Oxybutynin can be taken in both short-acting and long-acting forms, with the long-acting form taken once daily. While both medications can cause dry mouth and constipation, oxybutynin has a higher incidence of these side effects. Additionally, oxybutynin can be used in children as young as 5 years old, whereas darifenacin is not typically used in children. Both medications can cause dizziness and drowsiness, but oxybutynin has a higher risk of causing these side effects, especially in older adults. Lastly, darifenacin is generally not recommended for people over 65, while oxybutynin requires careful dosing in this age group to minimize side effects.
