SGLT2 inhibitor / gliptin combinations are used to treat Type 2 diabetes and lower the risk of cardiovascular events in certain people with Type 2 diabetes. These medications work by combining two types of medications: an SGLT2 inhibitor, which help your kidneys remove excess glucose (sugar) through your urine, and a gliptin (DPP-4 inhibitor), which increases natural insulin release and decrease glucose production in your liver. These combinations are available as oral tablets. Examples include empagliflozin / linagliptin (Glyxambi), dapagliflozin / saxagliptin (Qtern), and ertugliflozin / sitagliptin (Steglujan).
