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Compare Soliqua 100/33 vs. Ozempic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Soliqua 100/33
    Ozempic (semaglutide)
  • Soliqua 100/33
    Ozempic (semaglutide)

  • Summary of Soliqua 100/33 vs. Ozempic

    Summary for Insulin / GLP-1 agonist
    Prescription only

    Soliqua 100/33 is a combination medication for diabetes that contains insulin glargine (a long-acting insulin) and lixisenatide (a glucagon-like peptide-1 (GLP-1) receptor agonist). It helps manage blood sugar levels along with diet and exercise in adults with Type 2 diabetes. The medication comes as a prefilled pen and is injected under the skin once a day within 1 hour before you eat your first meal of the day. Soliqua 100/33 commonly causes stomach-related side effects like nausea and diarrhea.

    Summary for GLP-1 agonist
    Prescription only

    Ozempic (semaglutide) is a prescription injection that's used along with a nutritious diet and exercise to treat Type 2 diabetes in adults. It's also proven to lower the risk of heart attack, stroke, and death due to heart problems in adults with Type 2 diabetes and heart disease. Ozempic (semaglutide) belongs to the drug class known as GLP-1 agonists. The dosing is convenient because it's only injected under the skin once per week. Common side effects of this medication include nausea, vomiting, and diarrhea.

  • Indications of Soliqua 100/33 vs. Ozempic

    Indications for
    •Type 2 diabetes in adults
    Indications for
    •Type 2 diabetes
    •Lower the risk of heart attack, stroke, and death due to heart problems in adults with Type 2 diabetes and heart disease

  • Pros and Cons of Soliqua 100/33 vs. Ozempic

    Pros and Const for Insulin / GLP-1 agonist
    Pros
    •Lowers A1C by about 1%
    •Conveniently combines two medications in one injection
    •Injected under the skin once a day
    Cons
    •Risk of low blood sugar, especially if meals are skipped or delayed
    •Commonly causes stomach-related side effects like nausea and diarrhea
    •Must be taken within 1 hour before the first meal of the day
    Pros and Const for GLP-1 agonist
    Pros
    •Only given once per week
    •Available as prefilled pens for injection
    •Can switch injection days as long as the doses are separated by at least 2 days
    •Can store open and used pens at room temperature for up to 8 weeks
    Cons
    •Must be given as an injection under the skin
    •Commonly causes nausea, vomiting, and diarrhea
    •Risk of low blood sugar if it's taken with certain other diabetes medications (e.g., sulfonylureas, insulins)
    •Can't be used for Type 1 diabetes

  • Common Side Effects of Soliqua 100/33 vs. Ozempic

    Common Side Effects for
    •Nausea (10%)
    •Low blood sugar (8%)
    •Common cold-like symptoms (7%)
    •Diarrhea (7%)
    •Headache (5%)
    Common Side Effects for
    •Nausea (16-20%)
    •Diarrhea (9%)
    •Vomiting (5-9%)
    •Stomach pain (6-7%)
    •Constipation (3-5%)

  • Warnings of Soliqua 100/33 vs. Ozempic

    Common Side Effects for
    •Severe allergic reactions
    •Inflammation of the pancreas (pancreatitis)
    •Risk of high and low blood sugar levels
    •Dangerously low blood sugar levels (hypoglycemia)
    •Kidney damage
    •Low blood potassium levels
    •Fluid buildup and heart failure with certain diabetes medications
    •Gallbladder problems
    •Aspiration during anesthesia or sedation
    Common Side Effects for
    •Thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Eye problems
    •Low blood sugar (hypoglycemia) when taken with certain other diabetes medications
    •Dehydration and kidney problems
    •Severe allergic reactions
    •Gallbladder problems

  • Prices with our coupons for Soliqua 100/33 vs. Ozempic

    Learn more about Soliqua 100/33
    Learn more about Ozempic

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