Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Phentermine vs. Ozempic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Phentermine (Adipex-P)
    Ozempic (semaglutide)
  • Phentermine (Adipex-P)
    Ozempic (semaglutide)

  • Summary of Phentermine vs. Ozempic

    Summary for Sympathomimetic
    Prescription only

    Phentermine (Adipex-P) is an appetite suppressant. It's a prescription weight loss pill for people ages 17 years and older. This medication works best when it's part of a treatment plan that involves healthy diet and regular exercise. Phentermine (Adipex-P) is taken by mouth once daily, typically in the morning. Some of the more common side effects of this medication include dry mouth, trouble sleeping, and headache.

    Summary for GLP-1 agonist
    Prescription only

    Ozempic (semaglutide) is a prescription injection that's used along with a nutritious diet and exercise to treat Type 2 diabetes in adults. It's also proven to lower the risk of heart attack, stroke, and death due to heart problems in adults with Type 2 diabetes and heart disease. Ozempic (semaglutide) belongs to the drug class known as GLP-1 agonists. The dosing is convenient because it's only injected under the skin once per week. Common side effects of this medication include nausea, vomiting, and diarrhea.

  • Indications of Phentermine vs. Ozempic

    Indications for

    Short-term treatment for weight management in adults with a body mass index (BMI) of:

    •30 kg/m2 or greater; or
    •27 kg/m2 or greater, and with at least one other weight-related condition (e.g., high blood pressure, high blood sugar, high cholesterol)
    Indications for
    •Type 2 diabetes
    •Lower the risk of heart attack, stroke, and death due to heart problems in adults with Type 2 diabetes and heart disease

  • Pros and Cons of Phentermine vs. Ozempic

    Pros and Const for Sympathomimetic
    Pros
    •Can help you lose 5% to 10% of body weight
    •Usually taken by mouth once per day
    •Available as a lower-cost generic
    •Comes as tablets, capsules, and orally disintegrating tablets
    Cons
    •Most insurance companies don't cover the cost of phentermine (Adipex-P).
    •Has a risk of misuse and dependence since it's a stimulant medication that's similar to amphetamines
    •Might not be a good choice for people with high blood pressure
    •Should be avoided in children 16 years of age and younger, pregnant and breastfeeding women, and people with serious heart problems
    Pros and Const for GLP-1 agonist
    Pros
    •Only given once per week
    •Available as prefilled pens for injection
    •Can switch injection days as long as the doses are separated by at least 2 days
    •Can store open and used pens at room temperature for up to 8 weeks
    Cons
    •Must be given as an injection under the skin
    •Commonly causes nausea, vomiting, and diarrhea
    •Risk of low blood sugar if it's taken with certain other diabetes medications (e.g., sulfonylureas, insulins)
    •Can't be used for Type 1 diabetes

  • Common Side Effects of Phentermine vs. Ozempic

    Common Side Effects for
    •Dry mouth
    •Headache
    •Tremor
    •Constipation
    •Diarrhea
    •High blood pressure
    •Fast heart rate
    •Difficulty sleeping
    Common Side Effects for
    •Nausea (16-20%)
    •Diarrhea (9%)
    •Vomiting (5-9%)
    •Stomach pain (6-7%)
    •Constipation (3-5%)

  • Warnings of Phentermine vs. Ozempic

    Common Side Effects for
    •Not safe to combined with other weight loss medications
    •Phentermine not working well
    •Risk of misuse and dependence
    •Trouble concentrating or problem with coordination
    •Heart and lung problems
    •Risk of high blood pressure
    •Risk of low blood sugar in people with diabetes
    Common Side Effects for
    •Thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Eye problems
    •Low blood sugar (hypoglycemia) when taken with certain other diabetes medications
    •Dehydration and kidney problems
    •Severe allergic reactions
    •Gallbladder problems

  • Prices with our coupons for Phentermine vs. Ozempic

    Learn more about Phentermine
    Learn more about Ozempic

Compare other Weight Loss and Diabetes Type 2 drugs

Alli vs PhentermineBenzphetamine vs PhentermineContrave vs PhentermineDiethylpropion vs PhentermineLomaira vs Phentermine
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.