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Ubrelvy vs. Relpax

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ubrelvy (ubrogepant) and Relpax (eletriptan) are both medications used to treat migraine attacks with or without aura in adults. However, they belong to different medication classes. Ubrelvy is a calcitonin gene-related peptide (CGRP) receptor blocker, while Relpax is a triptan. Ubrelvy is taken as a 50 mg or 100 mg oral dose, with a second dose possible after 2 hours if needed, but not exceeding 200 mg per day. Relpax is taken as a 20 mg or 40 mg oral dose, with a second dose possible after 2 hours, but not exceeding 80 mg per day. Ubrelvy is not available as a generic, while Relpax is available in a lower-cost generic form. Common side effects of Ubrelvy include nausea, sleepiness, and dry mouth, whereas Relpax can cause dizziness, sleepiness, and nausea. Ubrelvy interacts with many medications, including certain antibiotics and seizure medications, while Relpax has serious interactions with ergot-containing medications and other triptans. Additionally, Relpax is not typically recommended for people with certain heart conditions or high blood pressure.

Ubrelvy

(ubrogepant)

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Eletriptan

(Relpax)

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Summary for Ubrelvy

Prescription only

Ubrelvy (ubrogepant) is a migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It can treat sudden migraine attacks in adults. Ubrelvy (ubrogepant) is a tablet you take by mouth. You take one dose when you feel a migraine starting. If needed, you can take a second dose at least 2 hours later. Your dose depends if Ubrelvy (ubrogepant) interacts with the other medications you take. Side effects include nausea and tiredness.

Indications for Ubrelvy

Pros and Cons for Ubrelvy

Pros

Cons

Common Side Effects for Ubrelvy

  • Nausea (up to 4%)
  • Sleepiness (up to 3%)
  • Dry mouth (up to 2%)

Warnings for Ubrelvy

  • Allergic reactions
  • High blood pressure
  • Raynaud's phenomenon

Summary for Relpax

Prescription only

Eletriptan, also known by its brand name Relpax, is a triptan that's a first-choice treatment option for adults who have migraine attacks with or without aura. This medication is available as a tablet that's taken by mouth at the first sign of a migraine attack. The dosage can be repeated 2 hours later if the migraine comes back or doesn't go away. Side effects include making you sleepy and dizzy. Eletriptan (Relpax) is available as a lower-cost generic.

Indications for Relpax

Pros and Cons for Relpax

Pros

Cons

  • Only available as a tablet that's swallowed whole
  • Not recommended for people with severe liver damage
  • Not known if it's safe or works well for children
  • Not used for preventing migraines or treating other types of headaches

Common Side Effects for Relpax

  • Dizziness (up to 6%)
  • Sleepiness (up to 6%)
  • Nausea (up to 5%)
  • Body weakness (up to 5%)
  • "Pins and needles" feeling in the arms or legs (3%)

Warnings for Relpax

  • Heart problems and high blood pressure
  • Stroke or other brain injury
  • Extreme narrowing of blood vessels
  • Worsened headaches if eletriptan (Relpax) is taken too often
  • Serotonin syndrome

Prices with our coupons for Ubrelvy vs. Relpax

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Ubrelvy10 tablets / 100mg
$1,086.36$1,384.47
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Eletriptan12 tablets / 40mg
$36.13$346.58
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