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Saxenda vs. Zepbound

Saxenda (generic name liraglutide) is a once-daily injection given under the skin that's used for weight loss. It's approved for certain adults and children ages 12 years and up. And it works best when used along with a balanced diet and exercise. This prescription weight loss medication is a glucagon-like peptide-1 (GLP-1) agonist. It works by slowing down your gut and making you feel less hungry. Saxenda (liraglutide) comes as a prefilled pen you use to inject your dose. Some common side effects include nausea, vomiting, and diarrhea.

• Weight loss and long-term weight management in:
  • People ages 12 years and older with a body weight greater than 132 lbs and obesity
  • Adults who are considered overweight with at least one weight-related condition (e.g., high blood pressure, Type 2 diabetes, high cholesterol)

Adults:

• Nausea (39%)
• Diarrhea (21%)
• Constipation (19%)
• Vomiting (16%)
• Injection site reaction (e.g., redness, itching, rash; 14%)
• Headache (14%)
• Low blood sugar in people with Type 2 diabetes (13%)
• Indigestion (10%)

Children 12 years and up:

• Nausea (42%)
• Vomiting (34%)
• Diarrhea (22%)
• Low blood sugar (15%)
• Stomach inflammation (13%)
• Dizziness (10%)

• Possible risk for thyroid cancer
• Inflammation of the pancreas (pancreatitis)
• Gallbladder problems
• Low blood sugar
• Faster heart rate
• Severe stomach side effects
• Kidney problems due to dehydration
• Allergic reactions
• Lung problems during anesthesia or deep sedation

Zepbound (tirzepatide) is an injectable medication that's used along with diet and exercise. It helps with weight loss in adults who meet criteria for weight management therapy. It's also approved to treat moderate-to-severe sleep apnea. This medication belongs to the drug class called GIP and GLP-1 agonists. The dosage is 1 injection under the skin once a week. Common side effects include nausea, diarrhea, and injection site reactions. Zepbound (tirzepatide) is only available as a brand-name medication.

In addition to a balanced diet and exercise plan:

• Weight loss and long-term weight management in adults considered obese or overweight with at least one weight-related condition (e.g., high blood pressure, Type 2 diabetes)
• Moderate-to-severe obstructive sleep apnea (OSA) in adults considered obese

• Nausea (25-29%)
• Diarrhea (19-23%)
• Constipation (11-17%)
• Vomiting (8-13%)
• Stomach pain (9-10%)
• Indigestion (9-10%)

• Risk of thyroid cancer
• Stomach problems
• Kidney damage
• Gallbladder problems
• Inflammation of the pancreas (pancreatitis)
• Allergic reactions
• Low blood sugar (hypoglycemia)
• Eye problems in people with Type 2 diabetes (diabetic retinopathy)
• Lung problems during general anesthesia or deep sedation
• Don't share Zepound KwikPens with anyone