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Lomaira vs. Contrave

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Lomaira

(phentermine)

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Contrave

(naltrexone / bupropion)

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Summary for Lomaira

Prescription only

Lomaira (phentermine) is a prescription appetite suppressant. It's used to help with weight loss and is approved for people ages 17 years and older. Lomaira (phentermine) is taken by mouth, typically three times per day. This medication is shorter-acting compared to Adipex-P (phentermine), which is taken once daily. Common side effects include dry mouth, trouble sleeping, and headache. You should avoid drinking alcohol while taking Lomaira (phentermine) because doing so can lead to serious risks, such as dizziness and heart problems.

Indications for Lomaira

Pros and Cons for Lomaira

Pros

  • Many people lose about 5% to 10% of body weight
  • Makes you feel less hungry soon after you start treatment
  • Taken by mouth

Cons

  • Taken multiple times a day
  • Harder to fall asleep if taken too close to bedtime
  • Short-term treatment only

Common Side Effects for Lomaira

  • Dry mouth
  • Headache
  • Tremor
  • Constipation
  • Diarrhea
  • High blood pressure
  • Fast heart rate
  • Difficulty sleeping

Warnings for Lomaira

  • Not safe to combined with other weight loss medications
  • Phentermine not working well
  • Risk of misuse and dependence
  • Trouble concentrating or problem with coordination
  • Heart and lung problems
  • Risk of high blood pressure
  • Risk of low blood sugar in people with diabetes

Summary for Contrave

Prescription only

Contrave is a combination medication that helps with weight loss for certain adults. It's taken along with a balanced diet and exercise plan. Contrave is a tablet with two active ingredients that help regulate your appetite. They are naltrexone (an opioid antagonist) and bupropion (a dopamine and norepinephrine reuptake inhibitor). Your dosage will slowly increase over the first 3 weeks. Then, you take the maintenance dose of two tablets by mouth twice a day. Some side effects are nausea, constipation, and headache. But it can also have serious risks, like unusual changes in behavior. Contrave is brand name only; there isn't a generic version available yet.

Indications for Contrave

Pros and Cons for Contrave

Pros

  • Comes as a tablet that you take by mouth
  • Might start to notice results in as early as 4 weeks (when taken along with a balanced diet and regular exercise)

Cons

  • Must take twice a day (after the dose ramp-up at the beginning)
  • Might raise your risk of unusual behavior and thoughts of self-harm
  • Interacts with a lot of medications

Common Side Effects for Contrave

  • Nausea (33%)
  • Constipation (19%)
  • Headache (18%)
  • Vomiting (11%)
  • Dizziness (10%)
  • Trouble sleeping (9%)
  • Dry mouth (8%)
  • Diarrhea (7%)

Warnings for Contrave

  • Risk of suicidal thoughts and behavior
  • Possible changes in thoughts, behavior, and mood
  • Seizures
  • Don't take Contrave with opioid medications
  • Higher blood pressure and faster heart rate
  • Liver problems
  • Mania (extreme enthusiasm or excitement)
  • Worsening of glaucoma in certain people
  • Potential risk of low blood sugar in people taking certain medications for Type 2 diabetes

Prices with our coupons for Lomaira vs. Contrave

Price Card Drug Icon
Lomaira30 tablets / 8mg
$16.62-
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Price Card Drug Icon
Contrave120 tablets / 8mg/90mg
$199.20$768.21
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