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Lamisil vs. Sporanox

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Terbinafine (Lamisil) and Sporanox (itraconazole) are both antifungal medications, but they are used to treat different types of fungal infections. Terbinafine is primarily used to treat fungal infections of the fingernails and toenails, while Sporanox is used to treat oral fungal infections like thrush. Terbinafine is taken once a day and can be taken with or without food, whereas Sporanox must be taken on an empty stomach for better absorption. Terbinafine can cause side effects like headache, rash, and upset stomach, and it can also lead to changes in taste or smell. On the other hand, Sporanox can cause nausea, diarrhea, and serious heart problems, including congestive heart failure. Both are available with a prescription, but terbinafine also has over-the-counter topical forms available. Additionally, Sporanox interacts with many other medications, which can be dangerous, while terbinafine has fewer interactions but can still affect other medications you might be taking.

Terbinafine

 

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Itraconazole

(Sporanox)

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Summary for Lamisil

Prescription only

Terbinafine is used to treat fingernail and toenail fungus in adults. It's a type of antifungal that helps get rid of the fungus. Terbinafine is a tablet you take once a day, but treatment can take many weeks to finish. Common side effects include headache, rash, and diarrhea. Terbinafine can interact with other medications, including certain antidepressants and beta blockers.

Indications for Lamisil

Pros and Cons for Lamisil

Pros

  • Works better to treat nail fungus than other treatment options
  • First-choice over other antifungals that are taken by mouth
  • Taken once a day, with or without food

Cons

  • Can take several weeks to work
  • Can cause loss of taste or smell (sometimes permanently)
  • Not recommended if you have liver problems

Common Side Effects for Lamisil

  • Headache (13%)
  • Rash (6%)
  • Diarrhea (6%)
  • Indigestion (4%)

Warnings for Lamisil

  • Liver damage
  • Changes to taste or smell
  • Symptoms of depression
  • Low white blood cell counts
  • Serious skin reactions
  • Lupus flare up
  • Clotting and bleeding problems

Summary for Sporanox

Prescription only

Itraconazole oral solution, also known by its brand name Sporanox, is an azole antifungal used to treat adults with fungal infections in the mouth and throat (oral thrush) and esophagus. You typically swish and swallow the dose once or twice a day on an empty stomach. Itraconazole (Sporanox) oral solution isn't a first-choice treatment option because it can interact with many other medications. It also has rare but serious side effects like heart failure, liver problems, and hearing loss.

Indications for Sporanox

Pros and Cons for Sporanox

Pros

  • Taken once to twice per day
  • Directly treats the infected areas
  • Good option for people who can't swallow pills

Cons

  • Not a first-choice treatment option
  • Commonly causes nausea, vomiting, and diarrhea
  • Interacts with many medications

Common Side Effects for Sporanox

  • Nausea (11%)
  • Diarrhea (11%)
  • Vomiting (7%)
  • Fever (7%)
  • Stomach pain (6%)

Warnings for Sporanox

  • Heart failure
  • Abnormal heart rhythm
  • Interactions with other medications
  • Liver damage
  • Hearing loss
  • Nerve damage

Prices with our coupons for Lamisil vs. Sporanox

Price Card Drug Icon
Terbinafine30 tablets / 250mg
$14.00$24.71
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Itraconazole60 capsules / 100mg
$47.41$522.37
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