Key takeaways
Terbinafine (Lamisil) and Jublia (efinaconazole) are both antifungal medications used to treat nail fungus, but they have some key differences. Terbinafine is taken orally as a tablet, while Jublia is a topical solution applied directly to the toenail. Terbinafine is typically taken once a day for 6 to 12 weeks, whereas Jublia is applied daily for about 11 months. Terbinafine can cause side effects like headache, rash, and upset stomach, and it has a risk of serious liver damage. Jublia, on the other hand, mainly causes local side effects like ingrown toenails and skin irritation. Terbinafine is available as a lower-cost generic, but Jublia does not have a generic version. Additionally, Jublia is only approved for toenail fungus, while terbinafine can treat both fingernail and toenail infections.
