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Imitrex vs. Dilantin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Sumatriptan (Imitrex) and phenytoin (Dilantin) are both prescription medications, but they treat different conditions. Sumatriptan is used to treat migraines in adults and works by tightening blood vessels in the brain to relieve pain. It is available as a lower-cost generic tablet. On the other hand, phenytoin is used to treat and prevent various types of seizures by decreasing abnormal signals between nerve cells in the brain. It is also available in a generic form. Sumatriptan is taken as needed for migraines, while phenytoin is taken regularly to maintain stable levels in the body. Sumatriptan can cause side effects like tingling and fatigue, whereas phenytoin can cause side effects such as dizziness, gum overgrowth, and changes in coordination. Additionally, phenytoin requires regular blood tests to monitor levels, while sumatriptan does not. Both medications have serious potential side effects and interactions, so it's important to discuss all your medications with your prescriber.

Sumatriptan

(Imitrex)

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Phenytoin

(Dilantin)

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Summary for Imitrex

Prescription only

Sumatriptan (Imitrex) is used to treat migraines with or without aura in adults. The medication is typically taken as a single dose for your migraine. But, it's possible that you can take it again 2 hours after the first dose if your migraine doesn't go away. Side effects of sumatriptan (Imitrex) include tingling or numbness of fingers or toes, feeling too warm or too cold, and fatigue. It can interact with antidepressants and other similar migraine medications. Sumatriptan (Imitrex) is available as a lower-cost generic tablet.

Indications for Imitrex

  • Treatment of migraine attacks with or without aura in adults

Pros and Cons for Imitrex

Pros

Cons

  • Can't use to prevent migraines
  • Must wait at least 2 hours after the first dose to take a second dose, if needed
  • Your migraines can get worse if you use this medication too often.
  • Unknown if it's safe or if it works well in children

Common Side Effects for Imitrex

  • Tingling or numbness of fingers or toes (3-5%)
  • Feeling too warm or too cold (2-3%)
  • Fatigue (2-3%)

Warnings for Imitrex

  • Heart problems and high blood pressure
  • Stroke or other brain injury
  • Extreme narrowing of blood vessels
  • Serotonin syndrome
  • Allergic reactions
  • Seizures

Summary for Dilantin

Prescription only

Phenytoin (Dilantin) is an antiepileptic medication used to treat and prevent seizures in adults and children. It comes in a capsule, chewable tablet, and liquid suspension that you take by mouth. The dose depends on your age, weight, and how well your seizures are controlled. Common side effects include trouble with coordination, unpredictable eye movements, and sleepiness. You’ll need regular blood tests to avoid toxicity, which is when the amount of medication in your body is too high and could be dangerous.

Indications for Dilantin

Pros and Cons for Dilantin

Pros

  • Available as a capsule, chewable tablet, and liquid suspension
  • Dose can be adjusted based on your response
  • Extended-release capsule can be taken once a day

Cons

  • Requires regular blood tests to check levels and determine the right dose
  • Common side effects include unpredictable eye movements and trouble with coordination
  • Can interact with a lot of other medications

Common Side Effects for Dilantin

  • Unpredictable eye movements
  • Trouble with coordination
  • Slurred speech
  • Sleepiness
  • Confusion

Warnings for Dilantin

  • Withdrawal seizures
  • Suicidal thoughts or behavior
  • Serious skin and allergic reactions
  • Heart problems
  • Liver problems
  • Lower blood cell count
  • Effects on Vitamin D and bone
  • Harm to unborn baby
  • High blood sugar levels
  • High phenytoin levels

Prices with our coupons for Imitrex vs. Dilantin

Price Card Drug Icon
Sumatriptan1 dose pack / 9 tablets of 100mg
$14.09$89.07
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Phenytoin90 capsules / 100mg
$22.54$52.99
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