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Imitrex vs. Amerge

Sumatriptan (Imitrex) is used to treat migraines with or without aura in adults. The medication is typically taken as a single dose for your migraine. But, it's possible that you can take it again 2 hours after the first dose if your migraine doesn't go away. Side effects of sumatriptan (Imitrex) include tingling or numbness of fingers or toes, feeling too warm or too cold, and fatigue. It can interact with antidepressants and other similar migraine medications. Sumatriptan (Imitrex) is available as a lower-cost generic tablet.

• Treatment of migraine attacks with or without aura in adults

• Tingling or numbness of fingers or toes (3-5%)
• Feeling too warm or too cold (2-3%)
• Fatigue (2-3%)

• Heart problems and high blood pressure
• Stroke or other brain injury
• Extreme narrowing of blood vessels
• Serotonin syndrome
• Allergic reactions
• Seizures

Naratriptan is a triptan that's used to treat migraines with or without aura in adults. While the brand name Amerge is no longer available, there's a generic version that you can get by prescription. Naratriptan is a tablet that's swallowed whole once, typically as a single dose. But you can take the medication again 4 hours later if the first dose didn't work to relieve your migraine. Side effects aren't common, but it might make you nauseous, sleepy, or dizzy.

• Treatment of migraine attacks with or without aura in adults

• Nausea (up to 5%)

• Heart problems and high blood pressure
• Stroke or other brain injury
• Extreme narrowing of blood vessels
• Worsened headaches if naratriptan is taken too often
• Serotonin syndrome