Key takeaways
Amphetamine sulfate (brands like Evekeo and Adzenys XR ODT) and Adderall (dextroamphetamine/amphetamine salts) are both stimulant medications used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. However, there are some key differences between them. Amphetamine sulfate contains only one type of amphetamine, while Adderall is a mix of different amphetamine salts, including amphetamine sulfate. This mixture in Adderall can sometimes make it more effective for some people. Amphetamine sulfate is also approved for short-term treatment of obesity, while Adderall is not. Both medications can cause side effects like trouble sleeping and loss of appetite, but they need to be taken exactly as prescribed to avoid misuse and dependence. Adderall is available as a lower-cost generic, while some forms of amphetamine sulfate are only available as brand-name medications. Both medications should be used with caution, especially if you have a history of heart problems or mental health issues.
