Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Epinastine (Elestat) and loratadine (Claritin) are both antihistamines used to treat allergy symptoms but there are some differences between them. Epinastine is specifically used to prevent eye itchiness from allergies and is available as an ophthalmic solution, while loratadine is used for short-term relief of allergy symptoms like runny nose and watery eyes and is available in oral forms. Epinastine is a prescription-only medication, whereas loratadine is available over-the-counter. Epinastine is applied directly to the eyes twice a day, while loratadine is typically taken by mouth once daily. Epinastine is approved for use in children as young as 2 years old, similar to loratadine, but loratadine offers more formulation options, such as chewable tablets and oral solutions. Common side effects of epinastine include a burning feeling in the eye and eye redness, while loratadine may cause headache and sleepiness. Additionally, loratadine should not be taken with other antihistamines like diphenhydramine (Benadryl) due to increased risk of side effects, whereas epinastine does not have such interactions.
Epinastine
Loratadine (Claritin)
Epinastine
Loratadine (Claritin)
Summary of Elestat vs. Claritin
Summary for Antihistamine
Prescription only
Epinastine hydrochloride is an antihistamine eye drop medication. It's used to prevent eye itchiness that's related to allergies. The eye drops are available by prescription for adults and children 2 years of age and older. The medication is placed directly into the eyes twice a day. Side effects include a burning feeling in the eye and eye redness.
Summary for Antihistamine
Loratadine (Claritin) is an over-the-counter antihistamine. It's used to ease allergy symptoms, such as runny nose or watery eyes, in adults and children. Loratadine (Claritin) is taken by mouth, typically once daily. It's available in different formulations, such as tablets and oral solution. Loratadine (Claritin) is considered a non-drowsy medication because it's less likely to cause sleepiness than some other antihistamines, such as diphenhydramine (Benadryl). Other side effects of this medication include headache and tiredness.