Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Epinastine (Elestat) and cromolyn (Crolom) are both eye drop medications used to treat eye allergy symptoms like itchiness and redness. They are similar in that they both help manage allergies, but they belong to different medication classes. Epinastine is an antihistamine and mast cell stabilizer, while cromolyn is solely a mast cell stabilizer. Epinastine is typically used twice a day, whereas cromolyn requires more frequent dosing, with 1 or 2 drops in each eye 4 to 6 times a day. Epinastine is approved for use in children as young as 2 years old, while cromolyn is for those over 4 years old. Epinastine works quickly, within about 5 minutes, but cromolyn may take a few days to weeks to show full effects. Common side effects of epinastine include a burning feeling in the eye and eye redness, while cromolyn may cause temporary stinging or burning. Both medications require a prescription and should not be used with contact lenses due to preservatives that can damage the lenses.
Epinastine
Cromolyn eye drop
Epinastine
Cromolyn eye drop
Summary of Elestat vs. Crolom
Summary for Antihistamine
Prescription only
Epinastine hydrochloride is an antihistamine eye drop medication. It's used to prevent eye itchiness that's related to allergies. The eye drops are available by prescription for adults and children 2 years of age and older. The medication is placed directly into the eyes twice a day. Side effects include a burning feeling in the eye and eye redness.
Summary for Mast cell stabilizer
Prescription only
Cromolyn eye drop is an ophthalmic drop that helps relieve long-term allergy symptoms related to the eye, such as eye itchiness, watery eyes, and eye redness. It belongs to a drug class called mast cell stabilizers. Cromolyn eye drop is for people over 4 years of age. The usual dosage is 1 or 2 drops in each eye 4 to 6 times a day. It typically takes a few days to a few weeks for symptom relief. The most common side effects are burning or stinging when you apply the eye drops.