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Cromolyn Coupon - Cromolyn 96 ampules of 100mg/5ml carton

cromolyn eye drop

Generic Crolom
Used for Allergic Conjunctivitis, Asthma, Mastocytosis

Cromolyn eye drop is an ophthalmic drop that helps relieve long-term allergy symptoms related to the eye, such as eye itchiness, watery eyes, and eye redness. It belongs to a drug class called mast cell stabilizers. Cromolyn eye drop is for people over 4 years of age. The usual dosage is 1 or 2 drops in each eye 4 to 6 times a day. It typically takes a few days to a few weeks for symptom relief. The most common side effects are burning or stinging when you apply the eye drops.

Reviewed by:Last reviewed on October 20, 2024
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What is Cromolyn eye drop?

What is Cromolyn eye drop used for?

How Cromolyn eye drop works

Cromolyn eye drop is a mast cell stabilizer. It works by making mast cells, a part of your immune system, less likely to release histamine. Histamine is a chemical in the body that causes allergic symptoms like itchy and red eyes.

By making the mast cells in the eye less likely to release histamine, cromolyn eye drop helps treat allergy symptoms in the eye.

Drug facts

Common BrandsCrolom(brand name no longer available)
Drug ClassMast cell stabilizer
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Cromolyn eye drop

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Temporary stinging or burning in your eye

Less Common Side Effects

  • Watery eyes
  • Itchy eyes
  • Dryness around the eye
  • Puffy eyes
  • Eye irritation

Cromolyn eye drop serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: trouble breathing, swelling in the throat or face, rash

Source: DailyMed

The following Cromolyn eye drop side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Coughing

difficulty in swallowing

hives or itching of skin

swelling of face, lips, or eyelids

wheezing or difficulty in breathing

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

Skin rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Diarrhea

headache

Less common

Abdominal pain

irritability

muscle pain

nausea

trouble in sleeping

Note: If the above side effects occur in patients with mastocytosis, they are usually only temporary and could be symptoms of the disease.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Pros and cons of Cromolyn eye drop

Pros

  • Helps both relieve and prevent long-term eye allergies
  • Most people have little to no side effects
  • Can be used in children as young as 4 years old

Cons

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Pharmacist tips for Cromolyn eye drop

pharmacist
  • Use cromolyn eye drop as often as your prescriber instructed you to. Be sure to use the eye drops at regular times each day. This medication works best when it's taken around the same times every day.
  • Wash your hands well with soap and water before you put cromolyn eye drop in your eyes. Don't let the dropper tip touch your eye or any other surface. Also don't touch the tip with your fingers. This will help prevent eye infections that can happen when you use eye drops that accidentally get contaminated with germs.
  • How to take cromolyn eye drops: Tilt your head back a little and look at the ceiling. With one hand, pull down your lower eyelid to make a pocket. Hold the bottle over the pocket and squeeze gently so a drop falls into the pocket. Then, close your eye and press one finger to the inner corner of your eye by your nose for a minute. This helps your eye absorb the drop. Repeat these steps for a second drop, if needed.
  • If you're using cromolyn eye drop at the same time as other eye medications, wait at least 5 minutes between each drop to give your eyes time to absorb each medication.
  • Don't wear contact lenses when you're putting in the cromolyn eye drop. The preservative in this medication, benzalkonium chloride, can get absorbed by your contacts and damage them. Your prescriber will tell you when you can wear your contact lenses again after you place the drops into your eyes.
  • It's also recommended that you generally avoid wearing contact lenses when your eyes are very itchy or red from allergies to prevent more irritation.
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Common questions about Cromolyn eye drop

No, cromolyn eye drop isn't a steroid. Instead, it's a mast cell stabilizer. Both steroid eye drops and cromolyn eye drops can help relieve eye allergy symptoms like redness and itching, but they work differently. Steroid eye drops are typically reserved for more severe symptoms. Your prescriber might recommend using cromolyn eye drop together with a steroid eye drop if your symptoms are severe.

Cromolyn eye drop isn't known to cause weight gain. Cromolyn eye drop works in your eyes to treat allergy symptoms there. Most of the medication from the eye drop isn't absorbed into your body. Speak to your primary care provider if you have concerns about your weight.

Cromolyn eye drop can start working to lessen eye itchiness, wateriness, and redness from allergies within a few days. But it can take up to 6 weeks after you start using it to see the full benefits of the medication. It's important to use the medication regularly every day for it to work the best for you. Ask a healthcare professional if you're looking for options for faster symptom relief as you wait for the cromolyn eye drop to start working. And contact your prescriber if you aren't noticing your symptoms getting better after a few days of using the cromolyn eye drop.

No, the cromolyn eye drop isn't available over the counter (OTC). You might be thinking of NasalCrom (cromolyn), which is an OTC nasal spray used for allergy symptoms related to the nose (e.g., runny, itchy nose). The cromolyn eye drop requires a prescription from a healthcare professional.

There isn't a set amount of time that you can use the cromolyn eye drop. Your prescriber will probably recommend that you continue with the eye drops if the medication is helping you feel better and if it isn't causing any side effects. Follow up with your prescriber regularly so they can make sure you still need to use this medication.

No. Cromolyn eye drop works best if you use the medication regularly. You typically need to use the cromolyn eye drop 4 to 6 times a day, so follow your prescriber's instructions carefully to get the most benefit from this medication.

Yes, cromolyn eye drop is available with a prescription from a healthcare professional. The brand names, Crolom and Opticrom, are no longer available. But there are still generic versions available on the market.

It's not completely clear whether cromolyn eye drop is safe to use while pregnant or breastfeeding because it isn't well studied. It also isn't known how much of the medication gets into breast milk. In general, cromolyn eye drop is typically used only if necessary during pregnancy and with caution while nursing. Discuss with your prescriber about the risks and benefits of cromolyn eye drop if you're pregnant or nursing before you start this medication.

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Risks and warnings for Cromolyn eye drop

Cromolyn eye drop can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Don't wear contact lenses

Cromolyn eye drop contains a preservative called benzalkonium chloride. This preservative can be absorbed by soft contact lenses and cause damage to them. It's best not to wear soft contact lenses while you're using the cromolyn eye drop. Speak with your prescriber or eye care specialist about when it's safe to start wearing contacts again.

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Cromolyn eye drop dosage

The average cost for 1 carton of 96 ampules of 100mg/5ml of Cromolyn eye drop is $138.20 with a free GoodRx coupon. This is 47.30% off the average retail price of $262.23.
eye dropperEye dropper
DosageQuantityPrice as low asPrice per unit
10ml of 4%1 eye dropper$14.81$14.81

Typical dosage for Cromolyn eye drop

Adults and children over 4 years old: Place 1 or 2 drops in each eye 4 to 6 times a day at regular time intervals.

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Interactions between Cromolyn eye drop and other drugs

Cromolyn eye drop may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Cromolyn eye drop. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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How much does Cromolyn eye drop cost?

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Gastrocrom (brand)
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$4.70

Cromolyn eye drop (generic)
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$4.70

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What are alternatives to Cromolyn eye drop?

There are a number of medications that your doctor can prescribe in place of Cromolyn eye drop. Compare a few possible alternatives below.
Cromolyn eye drop
Used for:
$4.70Lowest GoodRx priceView prices
Used for:
$13.85Lowest GoodRx priceView prices
Used for:
  • Allergy-related itchy eyes
$8.40Lowest GoodRx priceView prices
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Cromolyn eye drop images

colorless - Cromolyn Sodium 100mg/5mL Solution
This medicine is Colorless Carton.colorless - Cromolyn Sodium 100mg/5mL Solution
colorless - Cromolyn Sodium 100mg/5mL Solution
This medicine is Colorless Carton.colorless - Cromolyn Sodium 100mg/5mL Solution
colorless - Cromolyn Sodium 100mg/5mL Solution
This medicine is Colorless Carton.colorless - Cromolyn Sodium 100mg/5mL Solution
colorless - Cromolyn Sodium 100mg/5mL Solution
This medicine is Colorless Carton.colorless - Cromolyn Sodium 100mg/5mL Solution

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References

Best studies we found

Ahn, J., et al. (2021). Binding affinity of benzalkonium chloride on contact lens surfaces and the effects on their physical properties. Colloids and Surfaces B: Biointerfaces.

Gudgel, D. T. (2023). How to put in eye drops. American Academy of Ophthalmology.

SafeMedication. (n.d.). How to use eye drops.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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