Cromolyn eye drop is an ophthalmic drop that helps relieve long-term allergy symptoms related to the eye, such as eye itchiness, watery eyes, and eye redness. It belongs to a drug class called mast cell stabilizers. Cromolyn eye drop is for people over 4 years of age. The usual dosage is 1 or 2 drops in each eye 4 to 6 times a day. It typically takes a few days to a few weeks for symptom relief. The most common side effects are burning or stinging when you apply the eye drops.
Long-term eye allergy symptoms
Cromolyn eye drop is a mast cell stabilizer. It works by making mast cells, a part of your immune system, less likely to release histamine. Histamine is a chemical in the body that causes allergic symptoms like itchy and red eyes.
By making the mast cells in the eye less likely to release histamine, cromolyn eye drop helps treat allergy symptoms in the eye.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Check with your doctor as soon as possible if any of the following side effects occur:
Less common
Skin rash
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Abdominal pain
irritability
trouble in sleeping
Note: If the above side effects occur in patients with mastocytosis, they are usually only temporary and could be symptoms of the disease.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Helps both relieve and prevent long-term eye allergies
Most people have little to no side effects
Can be used in children as young as 4 years old
Takes longer to start working than other allergy eye drops
Have to use many times a day
Requires a prescription
Use cromolyn eye drop as often as your prescriber instructed you to. Be sure to use the eye drops at regular times each day. This medication works best when it's taken around the same times every day.
Wash your hands well with soap and water before you put cromolyn eye drop in your eyes. Don't let the dropper tip touch your eye or any other surface. Also don't touch the tip with your fingers. This will help prevent eye infections that can happen when you use eye drops that accidentally get contaminated with germs.
How to take cromolyn eye drops: Tilt your head back a little and look at the ceiling. With one hand, pull down your lower eyelid to make a pocket. Hold the bottle over the pocket and squeeze gently so a drop falls into the pocket. Then, close your eye and press one finger to the inner corner of your eye by your nose for a minute. This helps your eye absorb the drop. Repeat these steps for a second drop, if needed.
If you're using cromolyn eye drop at the same time as other eye medications, wait at least 5 minutes between each drop to give your eyes time to absorb each medication.
Don't wear contact lenses when you're putting in the cromolyn eye drop. The preservative in this medication, benzalkonium chloride, can get absorbed by your contacts and damage them. Your prescriber will tell you when you can wear your contact lenses again after you place the drops into your eyes.
It's also recommended that you generally avoid wearing contact lenses when your eyes are very itchy or red from allergies to prevent more irritation.
Cromolyn eye drop can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Cromolyn eye drop contains a preservative called benzalkonium chloride. This preservative can be absorbed by soft contact lenses and cause damage to them. It's best not to wear soft contact lenses while you're using the cromolyn eye drop. Speak with your prescriber or eye care specialist about when it's safe to start wearing contacts again.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
10ml of 4% | 1 eye dropper | $14.56 | $14.56 |
Adults and children over 4 years old: Place 1 or 2 drops in each eye 4 to 6 times a day at regular time intervals.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Temporary relief of allergy eye symptoms, such as itching and redness
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Ahn, J., et al. (2021). Binding affinity of benzalkonium chloride on contact lens surfaces and the effects on their physical properties. Colloids and Surfaces B: Biointerfaces.
Gudgel, D. T. (2023). How to put in eye drops. American Academy of Ophthalmology.
SafeMedication. (n.d.). How to use eye drops.
Sandoz Inc. (2021). Cromolyn sodium- cromolyn sodium solution/ drops [package insert]. DailyMed.
Sandoz Inc. (2021). Cromolyn sodium solution/ drops [package insert]. DailyMed.
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