Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Epinastine (Elestat) and ketorolac (Acular) are both eye drop medications. However, they belong to different medication classes. Epinastine is an antihistamine and mast cell stabilizer, while ketorolac is a non-steroidal anti-inflammatory drug (NSAID). Epinastine is specifically FDA-approved for preventing eye itchiness from allergies, whereas ketorolac is primarily used for pain and inflammation after eye surgeries, with itchy eyes from allergies being an off-label use. Epinastine is typically used twice a day, while ketorolac can be used 2 to 4 times a day depending on the condition. Both medications are available as generics and require a prescription. Common side effects of both medications include a burning feeling in the eye, eye redness, and blurry vision. Additionally, ketorolac may not be safe for those with NSAID or aspirin allergies and can slow healing if used with corticosteroid eye drops.
Epinastine
Ketorolac eye drop
Epinastine
Ketorolac eye drop
Summary of Elestat vs. Acular
Summary for Antihistamine
Prescription only
Epinastine hydrochloride is an antihistamine eye drop medication. It's used to prevent eye itchiness that's related to allergies. The eye drops are available by prescription for adults and children 2 years of age and older. The medication is placed directly into the eyes twice a day. Side effects include a burning feeling in the eye and eye redness.
Summary for NSAID
Prescription only
Ketorolac eye drop is a non-steroidal anti-inflammatory drug (NSAID). It's used to treat inflammation and pain after corneal or cataract surgery. Ketorolac eye drop can also help with itchy eyes from allergies, but it's not a first-choice medication for this condition. Ketorolac eye drop can be used by adults and children and is typically instilled 2 to 4 times per day, depending on the medical condition. Some common side effects include stinging, burning, and irritation after putting the eye drops. Ketorolac eye drop is available as a generic and as brand name medications (Acular, Acular LS, and Acuvail).