Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Epinastine (Elestat) and nedocromil (Alocril) are both eye drop medications used to treat allergy-related symptoms like itchy eyes. They are similar in that they both help with eye allergies, but they work differently. Epinastine is an antihistamine and mast cell stabilizer, while nedocromil is solely a mast cell stabilizer. Epinastine is typically used for preventing eye itchiness from allergies and is available as a lower-cost generic. It is applied as one drop in each eye twice a day. Nedocromil, on the other hand, is not a first-choice treatment and is used for itchy or watery eyes from allergies, with a typical dose of one or two drops in the affected eye(s) twice daily. Epinastine can be used in children as young as 2 years old, while nedocromil is approved for children 3 years and older. Common side effects of epinastine include a burning feeling in the eye and eye redness, whereas nedocromil often causes headaches and eye irritation. Both medications require a prescription and should not be used with contact lenses due to preservatives that can damage the lenses.
Epinastine
Alocril (nedocromil)
Epinastine
Alocril (nedocromil)
Summary of Elestat vs. Nedocromil
Summary for Antihistamine
Prescription only
Epinastine hydrochloride is an antihistamine eye drop medication. It's used to prevent eye itchiness that's related to allergies. The eye drops are available by prescription for adults and children 2 years of age and older. The medication is placed directly into the eyes twice a day. Side effects include a burning feeling in the eye and eye redness.
Summary for Mast cell stabilizer
Prescription only
Alocril (nedocromil) is an eye drop for eye-related allergy symptoms, such as itchiness or watery eyes. Typically, you place 1 to 2 drops into your eyes twice daily. But it's not a first-choice option for allergy symptoms. Some common side effects of this medication include headaches and eye irritation.